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Series GSE197723 Query DataSets for GSE197723
Status Public on Mar 03, 2022
Title In vitro methylation studies in multiple human cell types [HumanMethylation850 array]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary An Infinium microarray (Illumina Infinium HumanMethylation850 BeadChip) was used to generate DNA methylation data from human tissue samples.
 
Overall design n=317 samples. Different sources of human DNA: skin, basal cell carcinoma, keratinocytes, fibroblasts, endothelial cells, keratinocyte stem cells, induced pluripotent stem cells, HUVEC, HCAEC, neural progenitor. These cells were exposed to different conditions and treatments: CCCP (Mitochondrial oxidative phosphorylation uncoupler), bezafibrate, hTERT immortalization, chronic radiation, rapamycin.
Genome annotations of the array can be downloaded from https://support.illumina.com/downloads/infinium_humanmethylation450_product_files.html
 
Contributor(s) Horvath S, Raj K
Citation(s) 37688320
Submission date Mar 01, 2022
Last update date Oct 26, 2023
Contact name Steve Horvath
E-mail(s) shorvath@altoslabs.com
Organization name University of California, Los Angeles
Department Human Genetics
Lab Horvath
Street address 695 Charles E. Young Drive South, Box 708822
City Los Angeles
State/province CA
ZIP/Postal code 90095-7088
Country USA
 
Platforms (1)
GPL23976 Illumina Infinium HumanMethylation850 BeadChip
Samples (317)
GSM5928812 Sample1.Skin.203786210088_R07C01
GSM5928813 Sample2.Paired BCC.203786210088_R08C01
GSM5928814 Sample3.Skin.203786210060_R07C01
This SubSeries is part of SuperSeries:
GSE197724 In vitro methylation studies in multiple human cell types
Relations
BioProject PRJNA811635

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE197723_Explanation_of_characteristic_variables.docx.gz 13.8 Kb (ftp)(http) DOCX
GSE197723_RAW.tar 4.4 Gb (http)(custom) TAR (of IDAT)
GSE197723_datBetaNormalized.csv.gz 2.2 Gb (ftp)(http) CSV
Processed data are available on Series record
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