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Status |
Public on Mar 01, 2023 |
Title |
Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing |
Organism |
Mus musculus |
Experiment type |
Other
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Summary |
State-of-the-art algorithms for m6A detection and quantification via nanopore direct RNA sequencing have been continuously developed, little is known about their capacities and limitations, which makes a comprehensive assessment in urgent need. Therefore, we performed comprehensive benchmarking of 10 computational tools relying on current-based and base-calling “errors” strategies for m6A detection by nanopore sequencing.
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Overall design |
m6A detection of wild type and Mettl3 knock-out mouse embryonic stem cells.
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Contributor(s) |
Zhong Z, Xie Y, Zhang Z, Luo G |
Citation(s) |
37019930 |
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Submission date |
Jan 28, 2022 |
Last update date |
May 02, 2023 |
Contact name |
Zhendong Zhong |
E-mail(s) |
zhongzhd@mail2.sysu.edu.cn
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Phone |
19806835958
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Organization name |
Sun Yat-sen University
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Department |
School of Life Sciences
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Street address |
Xingangxi Roda 135#
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City |
Guangzhou |
State/province |
Guangdong |
ZIP/Postal code |
510275 |
Country |
China |
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Platforms (1) |
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Samples (2) |
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Relations |
BioProject |
PRJNA801506 |