|
| Status |
Public on Aug 30, 2022 |
| Title |
Gene expression changes in beta-blocker treated neonatal hearts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The regeneration potential of the mammalian heart is limited. We found that treatment of beta-blocker robustly enhanced cardiomyocyte proliferation and promoted cardiac regeneration post myocardial infarction. To investigate the gene expression changes, we performed RNA-seq using the hearts treated with beta-blocker for 7 days.
|
| |
|
| Overall design |
mRNA profiles of neonatal control and beta-blocker treated hearts at P7
|
| |
|
| Contributor(s) |
Sakabe M, Xin M |
| Citation(s) |
36479975 |
| |
| Submission date |
Oct 19, 2021 |
| Last update date |
Jan 11, 2023 |
| Contact name |
Mei Xin |
| E-mail(s) |
mei.xin@cchmc.org
|
| Phone |
5138033464
|
| Organization name |
Cincinnati Children's Hospital
|
| Department |
EHCB
|
| Lab |
Xin
|
| Street address |
3333 Burnet Avenue
|
| City |
Cincinnati |
| State/province |
OH |
| ZIP/Postal code |
45249 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA772616 |
| SRA |
SRP342064 |
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