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Status |
Public on Jul 02, 2009 |
Title |
Bio-electrospraying the nematode Caenorhabditis elegans |
Organism |
Caenorhabditis elegans |
Experiment type |
Expression profiling by array
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Summary |
Bio-electrospray, the direct jet-based cell handling apporach, is able to handle a wide range of cells. Studies at the genomic, genetic, and the physiological level have shown that, post-treatment, cellular integrity is unperturbed and a high percentage (>70%, compared to control) of cells remain viable. Although, these results are impressive, it may be argued that cell based systems are oversimplistic. This study utilizing a well characterised multicellular model organism, the non-parasitic nematode Caenorhabditis elegans. Nematodes were subjected to bio-electrosprays to demonstrate that bio-electrosprays can be safely applied to nematodes.
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Overall design |
The global transcriptomic response was compared in control nematodes (negative control), heat shocked nematodes (positive control). and nematodes subjected to bio-electrospray.
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Contributor(s) |
Mongkoldhumrongkul N, Swain SC, Jayasinghe SN, Sturzenbaum SR |
Citation(s) |
19776148 |
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Submission date |
Jul 01, 2009 |
Last update date |
Jul 06, 2016 |
Contact name |
Stephen Sturzenbaum |
E-mail(s) |
stephen.sturzenbaum@kcl.ac.uk
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Organization name |
King's College London
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Department |
Analytical, Environmental and Forensic Sciences
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Street address |
150 Stamford Street
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City |
London |
ZIP/Postal code |
SE1 9NH |
Country |
United Kingdom |
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Platforms (1) |
GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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Samples (3) |
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Relations |
BioProject |
PRJNA117707 |
Supplementary file |
Size |
Download |
File type/resource |
GSE16915_RAW.tar |
4.6 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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