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| Status |
Public on Jan 27, 2021 |
| Title |
Gene expression Profiles following mild and severe muslce contusion in rats |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
We used microarray to investigate gene expression profiles of mildly and severely contused muscle and aimed to provide more information about the molecular mechanisms underlying the repair process. Moreover, we have an attempt to identify useful markers with time-dependent expression for wound age estimation.
Animal models of muscle contusion (mild and severe) were developed to investigate the cellular response to mechanical muscle damage
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| Overall design |
A total of 33 rats were divided randomly into control (n = 3), mild contusion (n = 15), and severe contusion (n = 15) groups; the contusion groups were further divided into five subgroups (1, 3, 24, 48, and 168 h post-injury; n = 3 per subgroup). Total RNA was isolated from muscle tissue for analysis by microarray using the Affymetrix rat Gene 2.0 ST chip.
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| Contributor(s) |
Sun J, Bai R |
| Citation(s) |
33398324 |
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| Submission date |
Dec 02, 2020 |
| Last update date |
Jan 27, 2021 |
| Contact name |
Jun-hong Sun |
| E-mail(s) |
junhong.sun@sxmu.edu.cn
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| Organization name |
Shanxi Medical University
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| Department |
School of Forensic Medicine
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| Street address |
98 University Street, Yuci District, Jinzhong
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| City |
Jinzhong |
| State/province |
Shanxi Province |
| ZIP/Postal code |
030604 |
| Country |
China |
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| Platforms (1) |
| GPL17117 |
[RaGene-2_0-st] Affymetrix Rat Gene 2.0 ST Array [transcript (gene) version] |
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| Samples (33)
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| GSM4954574 |
skeletal muscle of control group, biological rep1 |
| GSM4954575 |
skeletal muscle of control group, biological rep2 |
| GSM4954576 |
skeletal muscle of control group, biological rep3 |
| GSM4954577 |
mildly contused muscel at 1h , biological rep1 |
| GSM4954578 |
mildly contused muscel at 1h , biological rep2 |
| GSM4954579 |
mildly contused muscel at 1h , biological rep3 |
| GSM4954580 |
mildly contused muscel at 3h , biological rep1 |
| GSM4954581 |
mildly contused muscel at 3h , biological rep2 |
| GSM4954582 |
mildly contused muscel at 3h , biological rep3 |
| GSM4954583 |
mildly contused muscel at 24h , biological rep1 |
| GSM4954584 |
mildly contused muscel at 24h , biological rep2 |
| GSM4954585 |
mildly contused muscel at 24h , biological rep3 |
| GSM4954586 |
mildly contused muscel at 48h , biological rep1 |
| GSM4954587 |
mildly contused muscel at 48h , biological rep2 |
| GSM4954588 |
mildly contused muscel at 48h , biological rep3 |
| GSM4954589 |
mildly contused muscel at 168h , biological rep1 |
| GSM4954590 |
mildly contused muscel at 168h , biological rep2 |
| GSM4954591 |
mildly contused muscel at 168h , biological rep3 |
| GSM4954592 |
severely contused muscel at 1h , biological rep1 |
| GSM4954593 |
severely contused muscel at 1h , biological rep2 |
| GSM4954594 |
severely contused muscel at 1h , biological rep3 |
| GSM4954595 |
severely contused muscel at 3h , biological rep1 |
| GSM4954596 |
severely contused muscel at 3h , biological rep2 |
| GSM4954597 |
severely contused muscel at 3h , biological rep3 |
| GSM4954598 |
severely contused muscel at 24h , biological rep1 |
| GSM4954599 |
severely contused muscel at 24h , biological rep2 |
| GSM4954600 |
severely contused muscel at 24h , biological rep3 |
| GSM4954601 |
severely contused muscel at 48h , biological rep1 |
| GSM4954602 |
severely contused muscel at 48h , biological rep2 |
| GSM4954603 |
severely contused muscel at 48h , biological rep3 |
| GSM4954604 |
severely contused muscel at 168h , biological rep1 |
| GSM4954605 |
severely contused muscel at 168h , biological rep2 |
| GSM4954606 |
severely contused muscel at 168h , biological rep3 |
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| Relations |
| BioProject |
PRJNA682219 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE162565_RAW.tar |
255.9 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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