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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 29, 2022 |
| Title |
Time series RNA-Seq of the olfactory epithelia of the mouse |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
A series of RNA-Seq experiment were conducted to study the transcriptome changes of olfactory sensory neurons during the critical period. We conducted RNA-seq of the olfactory epithelia at P0, P3, P7, P14, and P21 to identify the gene expression changes in the olfactory epithelia. We also performed RNA-Seq experiment of the olfactory epithelia from Kir2.1 transgenic mice at the same time points to understand the effect of neural activity deprivation on the transcriptome.
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| Overall design |
For wildtype animal experiment, mouse olfactory epithelia samples from 4 replicates of P0 mice, 3 replicates of P3 mice, 3 replicates of P5 mice, 4 replicates of P7 mice, 3 replicates of P10 mice, 3 replicates of P14 mice, and 3 replicates of P21 mice. For Kir2.1 experiment, 4 replicates of P0 Kir2.1 mice, 3 replicates of P3 Kir2.1 mice, 3 replicates of P5 mice, 4 replicates of P7 Kir2.1 mice, 4 replicates of P10 Kir2.1 mice, 3 replicates of P14 Kir2.1 mice, and 3 replicates of P21 Kir2.1 mice were used.
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| Contributor(s) |
Wu Y, Ma L, Blanck J, Scott A, Chen SC, Hassan H, Hall K, Perera A, Yu CR |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Mar 24, 2020 |
| Last update date |
Aug 29, 2022 |
| Contact name |
Congrong Ron Yu |
| E-mail(s) |
cry@stowers.org
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| Phone |
816-926-4334
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| Organization name |
Stowers Insitute for Medical Research
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| Lab |
Yu
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| Street address |
1000 E 50th St
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| City |
Kansas City |
| State/province |
Missouri |
| ZIP/Postal code |
64110-2262 |
| Country |
USA |
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| Platforms (1) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
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| Samples (47)
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| This SubSeries is part of SuperSeries: |
| GSE147463 |
Molecular Control of Circuit Plasticity and the Permanence of Imprinted Odor Memory |
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| Relations |
| BioProject |
PRJNA614925 |
| SRA |
SRP253854 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE147459_RSEM_TPM_table.csv.gz |
3.1 Mb |
(ftp)(http) |
CSV |
| GSE147459_star_count.csv.gz |
1.9 Mb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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