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| Status |
Public on Feb 28, 2020 |
| Title |
Differential gene expression in circulating CD14+ monocytes indicates the prognosis of critically ill patients with sepsis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Critical illness and sepsis are characterized by drastic changes in the systemic innate immune response, particularly involving monocytes. Here we prospectively analyzed the gene expression profile of circulating CD14+ monocytes of selected samples by RNA Sequencing.
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| Overall design |
Analysis of the RNA expression of circulating CD14+ monocytes of healthy volunteers and intensive care unit (ICU) patients with and without sepsis.
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| Contributor(s) |
Liepelt A, Hohlstein P, Gussen H, Xue J, Aschenbrenner AC, Ulas T, Buendgens L, Warzecha KT, Bartneck M, Luedde T, Trautwein C, Schultze JL, Koch A, Tacke F |
| Citation(s) |
31906585 |
| |
| Submission date |
Nov 04, 2019 |
| Last update date |
Feb 28, 2020 |
| Contact name |
Joachim Schultze |
| E-mail(s) |
j.schultze@uni-bonn.de
|
| Organization name |
LIMES (Life and Medical Sciences Center Genomics and Immunoregulation)
|
| Department |
Genomics and Immunoregulation
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| Street address |
Carl-Troll-Strasse 31
|
| City |
Bonn |
| State/province |
NRW |
| ZIP/Postal code |
53115 |
| Country |
Germany |
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| Platforms (1) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
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| Samples (13)
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| Relations |
| BioProject |
PRJNA587525 |
| SRA |
SRP228564 |
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