|
| Status |
Public on Jul 18, 2020 |
| Title |
Using bone marrow stromal cells as micro-environmental sensors identifies IL-6 and TGFa signalling as regulators of declining erythropoiesis and lymphopoiesis during hematopoietic ageing |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation(s) |
32796847 |
| |
| Submission date |
May 08, 2019 |
| Last update date |
Aug 28, 2020 |
| Contact name |
Claus Nerlov |
| E-mail(s) |
claus.nerlov@imm.ox.ac.uk
|
| Organization name |
Weatheral Institute of Molecular Medicine
|
| Department |
MRC Molecular Haematology Unit
|
| Lab |
Nerlov Laboratory
|
| Street address |
John Radcliffe Hospital, University of Oxford
|
| City |
Oxford |
| ZIP/Postal code |
OX3 9DS |
| Country |
United Kingdom |
| |
|
| Platforms (2) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (50)
|
|
| This SuperSeries is composed of the following SubSeries:
|
| GSE130717 |
Transcriptomic alterations of erythroid progenitors during ageing |
| GSE130885 |
Transcriptomic alterations of stromal cells during ageing |
| GSE130886 |
Effect of IL6 inhibition on the gene expression of erythroid progenitors in aged mice |
| GSE130896 |
Effect of TGFbeta inibition on the transcriptional profile of aged hematopoietic stem and progenitor cells |
|
| Relations |
| BioProject |
PRJNA541918 |
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