|
| Status |
Public on Jan 27, 2021 |
| Title |
WGBS of WT and Smchd1-KO ES cells |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
We performed the whole genome bisulfite sequencing to detect the DNA methylation between the wild type ES cells and Smchd1 mutant ES cells
|
| |
|
| Overall design |
Three biological replicates per genotype; DNA was isolated individually from each replicate; three samples for WT and Smchd-KO mutant were sequenced twice.
|
| |
|
| Contributor(s) |
Huang Z, Pfeifer G |
| Citation(s) |
33523915 |
|
https://doi.org/10.1126/sciadv.abb9149
|
| |
| Submission date |
Feb 12, 2019 |
| Last update date |
Feb 08, 2021 |
| Contact name |
Gerd P Pfeifer |
| E-mail(s) |
gerd.pfeifer@vai.org
|
| Organization name |
Van Andel Research Institute
|
| Department |
Center for Epigenetics
|
| Street address |
333 Bostwick Ave NE
|
| City |
Grand Rapids |
| State/province |
MI |
| ZIP/Postal code |
49503 |
| Country |
USA |
| |
|
| Platforms (1) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE126468 |
The chromosomal protein SMCHD1 regulates DNA methylation by antagonizing TET proteins |
|
| Relations |
| BioProject |
PRJNA521987 |
| SRA |
SRP185723 |
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