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Series GSE124876 Query DataSets for GSE124876
Status Public on Mar 01, 2019
Title Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The density of the extracellular matrix has a dramatic impact on the gene expression profile of T cells and macrophages. This may reflect impaired immune response of T cells and macrophages in solid tumors.
Overall design Quantification of RNA expression in human PBMCs enriched for T cells through the selection of non-adhenernt cells and a murine macrophage cell line (RAW 264.7) cultured in different densities of extracellular matrix (Type I collagen). T cells were isolated from PBMCs
Contributor(s) Madsen DH, Grøntved L
Citation(s) 30867051
Submission date Jan 09, 2019
Last update date Aug 08, 2019
Contact name Lars Grøntved
Phone +45 24 60 14 06
Organization name University of Southern Denmark
Department Biochemistry and Molecular Biology
Street address Campusvej 55
City Odense
ZIP/Postal code 5230
Country Denmark
Platforms (2)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (18)
GSM3557785 Tcell HDM rep1
GSM3557786 Tcell HDM rep2
GSM3557787 Tcell HDM rep3
BioProject PRJNA514057
SRA SRP178203

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE124876_Macrophage_RPKM.txt.gz 1.0 Mb (ftp)(http) TXT
GSE124876_Tcell_RPKM.txt.gz 2.7 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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