|
| Status |
Public on May 13, 2019 |
| Title |
Transcriptome time course of mouse acute myeloid leukemia cells upon PU.1 restoration and knockdown |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We have utilized advanced RNAi technology to dynamically restore and subsequently knock down endogenous PU.1 expression in p53-deficient AML cells, which respectively causes differentiation and de-differentiation
|
| |
|
| Overall design |
RNA-seq was performed on AML246 cells following Dox treatment or withdrawal over a 24 day time course
|
| |
|
| Contributor(s) |
Liu R, Oxley EP, Dickins RA, Ritchie ME |
| Citation(s) |
31374198 |
| |
| Submission date |
Jan 09, 2018 |
| Last update date |
Aug 05, 2019 |
| Contact name |
Ruijie Liu |
| E-mail(s) |
cynthia.liu@adelaide.edu.au
|
| Organization name |
the university of Adelaide
|
| Street address |
Mudla Wirra Rd
|
| City |
Roseworthy |
| State/province |
South Australia |
| ZIP/Postal code |
5371 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (16)
|
|
| This SubSeries is part of SuperSeries: |
| GSE76934 |
Reversible transitions between transformed and differentiated states in AML |
|
| Relations |
| BioProject |
PRJNA429228 |
| SRA |
SRP128540 |
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