|
| Status |
Public on Dec 15, 2020 |
| Title |
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
A CRISPR-Cas9-based zebrafish screen for candidate genes causative of human heart disease uncovers cardiac defects when perturbing Bcl9.
|
| |
|
| Overall design |
bcl9∆29/29
|
| |
|
| Contributor(s) |
Mosimann C, Felker A, Chiavacci E, Cabello E |
| Citation missing |
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| |
| Submission date |
Dec 18, 2017 |
| Last update date |
Dec 15, 2020 |
| Contact name |
Christian Mosimann |
| E-mail(s) |
christian.mosimann@imls.uzh.ch
|
| Organization name |
University of Zürich
|
| Department |
Institute of Molecular Life Sciences
|
| Lab |
Mosimann Lab
|
| Street address |
Winterthurerstrasse 190
|
| City |
Zürich |
| ZIP/Postal code |
8057 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL18413 |
Illumina HiSeq 2500 (Danio rerio) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA422899 |
| SRA |
SRP126965 |
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