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Series GSE104601 Query DataSets for GSE104601
Status Public on Oct 04, 2020
Title Investigating the effect of inflammatory conditions on acetaminophen-induced liver injury using 3D human multicellular microtissues
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To investigate the molecular mechanisms of the inflammation-mediated exacerbation of increased acetaminophen (APAP) toxicity.
 
Overall design 3D-co-cultured microtissues (MTs), consisting of primary human hepatocytes (PHH) and Kupffer cells (KCs), were exposed to 0, 0.5, 5 and 10 mM acetaminophen for 24h with/without lipopolysaccharide (LPS).
 
Contributor(s) Jiang J, Kelm JM, van Herwijnen MH, Jennen DG, Kleinjans JC, de Kok TM
Citation(s) 31059760
Submission date Oct 04, 2017
Last update date Jul 25, 2021
Contact name Jian Jiang
E-mail(s) j.jiang@maastrichtuniversity.nl
Phone 0684063016
Organization name Maastricht University
Department Toxicogenomics
Street address Maastricht University
City Maastricht
ZIP/Postal code 6200 MD
Country Netherlands
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (24)
GSM2803969 MT_medium_without_LPS_24h_exp1
GSM2803970 MT_medium_without_LPS_24h_exp2
GSM2803971 MT_medium_without_LPS_24h_exp3
Relations
BioProject PRJNA413194

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE104601_RAW.tar 296.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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