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Status |
Public on Aug 08, 2018 |
Title |
Profiling of untreated and residual murine BCC after Hedgehog Pathway Inhibitor |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
RNA was isolated from laser capture micro-dissected (LCM) tumour nests from fresh frozen skin of K14Cre-ER; Ptch1fl/fl; p53fl/fl mice either before (untreated) or after (treated) 28 days of twice a day vismodegib dosing at 75mg/kg body weight by oral gavage. The "SAMPLE_ID" sample characteristic is a sample identifier internal to Genentech. The ID of this project in Genentech's ExpressionPlot database is PRJ0014355
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Overall design |
Gene expression profiling of tumour cells from BCC mice before and after 28 days of vismodegib treatment
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Contributor(s) |
Piskol R, Biehs B |
Citation(s) |
30297801 |
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Submission date |
Jul 17, 2017 |
Last update date |
Jul 25, 2021 |
Contact name |
Robert Piskol |
E-mail(s) |
piskolr@gene.com
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Organization name |
Genentech Inc.
|
Department |
Bioinformatics
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Street address |
1 DNA Way
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City |
South San Francisco |
State/province |
CA |
ZIP/Postal code |
94080 |
Country |
USA |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (15)
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This SubSeries is part of SuperSeries: |
GSE116966 |
Characterizing the molecular changes of Basal Cell Carcinoma during vismodegib treatment |
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Relations |
BioProject |
PRJNA394698 |
SRA |
SRP112535 |