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LAMA2 laminin subunit alpha 2 [ Coturnix japonica (Japanese quail) ]

Gene ID: 107311739, updated on 14-Mar-2024

Summary

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Gene symbol
LAMA2
Gene description
laminin subunit alpha 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Coturnix japonica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Perdicinae; Coturnix
Orthologs
human mouse all
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Genomic context

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See LAMA2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
67
Annotation release Status Assembly Chr Location
101 current Coturnix japonica 2.1 (GCF_001577835.2) 3 NC_029518.1 (52698739..52982053, complement)

Chromosome 3 - NC_029518.1Genomic Context describing neighboring genes Neighboring gene L3MBTL histone methyl-lysine binding protein 3 Neighboring gene Rho GTPase activating protein 18 Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene uncharacterized LOC116653269

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_029518.1 Chromosome 3 Reference Coturnix japonica 2.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Coturnix japonica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Coturnix japonica 2.1 Primary Assembly

Genomic

  1. NC_029518.1 Reference Coturnix japonica 2.1 Primary Assembly

    Range
    52698739..52982053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032443478.1 → XP_032299369.1  laminin subunit alpha-2 isoform X3

    Conserved Domains (12) summary
    smart00136
    Location:40 → 287
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:970 → 1014
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1232 → 1400
    LamB; Laminin B domain
    COG1196
    Location:1852 → 2185
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:920 → 968
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3005 → 3157
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1630 → 1887
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2074 → 2208
    Laminin_II; Laminin Domain II
    pfam00052
    Location:585 → 725
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1063 → 1111
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2857 → 2985
    Laminin_G_1; Laminin G domain
    cl22855
    Location:301 → 434
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_015858546.2 → XP_015714032.1  laminin subunit alpha-2 isoform X5

    Conserved Domains (14) summary
    smart00180
    Location:970 → 1014
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1232 → 1400
    LamB; Laminin B domain
    cd00055
    Location:920 → 968
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3021 → 3173
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:585 → 714
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1063 → 1111
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2873 → 3001
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:52 → 287
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam00261
    Location:1853 → 2155
    Tropomyosin; Tropomyosin
    pfam06008
    Location:1628 → 1887
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2074 → 2210
    Laminin_II; Laminin Domain II
    cl21504
    Location:1416 → 1444
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl21509
    Location:1850 → 2010
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
    cl22855
    Location:301 → 434
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  3. XM_015858545.2 → XP_015714031.1  laminin subunit alpha-2 isoform X4

    Conserved Domains (14) summary
    smart00180
    Location:970 → 1014
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1232 → 1400
    LamB; Laminin B domain
    cd00055
    Location:920 → 968
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3007 → 3159
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:585 → 714
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1063 → 1111
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2859 → 2987
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:52 → 287
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam00261
    Location:1853 → 2155
    Tropomyosin; Tropomyosin
    pfam06008
    Location:1628 → 1887
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2074 → 2210
    Laminin_II; Laminin Domain II
    cl21504
    Location:1416 → 1444
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl21509
    Location:1850 → 2010
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
    cl22855
    Location:301 → 434
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  4. XM_015858544.2 → XP_015714030.1  laminin subunit alpha-2 isoform X2

    Conserved Domains (13) summary
    smart00180
    Location:970 → 1014
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1232 → 1400
    LamB; Laminin B domain
    cd00055
    Location:920 → 968
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3025 → 3177
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:585 → 714
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1063 → 1111
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2877 → 3005
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:52 → 287
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam00261
    Location:1853 → 2155
    Tropomyosin; Tropomyosin
    pfam06008
    Location:1628 → 1887
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2074 → 2210
    Laminin_II; Laminin Domain II
    cl21509
    Location:1850 → 2010
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
    cl22855
    Location:301 → 434
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  5. XM_015858543.2 → XP_015714029.1  laminin subunit alpha-2 isoform X1

    Conserved Domains (13) summary
    smart00180
    Location:1058 → 1102
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1320 → 1488
    LamB; Laminin B domain
    cd00055
    Location:920 → 965
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3113 → 3265
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00052
    Location:585 → 714
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1151 → 1199
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:2965 → 3093
    Laminin_G_1; Laminin G domain
    pfam00055
    Location:52 → 287
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam00261
    Location:1941 → 2243
    Tropomyosin; Tropomyosin
    pfam06008
    Location:1716 → 1975
    Laminin_I; Laminin Domain I
    pfam06009
    Location:2162 → 2298
    Laminin_II; Laminin Domain II
    cl21509
    Location:1938 → 2098
    ApoLp-III_like; Apolipophorin-III and similar insect proteins
    cl22855
    Location:301 → 434
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
Nucleotide Protein
Heading Accession and Version

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