Conserved Protein Domain Family
Laminin_I

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pfam06008: Laminin_I 
Laminin Domain I
coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Statistics
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PSSM-Id: 310534
Aligned: 8 rows
Threshold Bit Score: 297.787
Created: 22-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q60675       1589 TMNIN-LTGPLPAPYKILYGLENTTQELKHLLSPQRAPERLIQLAEGNVNTLVMETNELLTRATKVTADGEQTGQDAERT 1667 house mouse
Q16363        298 VLSVSsGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDT 377  human
O15230       2192 LRGINaSSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEAT 2271 human
XP_017456642 1846 LQGLSvSTGALEQIRHVEMQAKDLRNQLLGFRSAISSHGSKMDGLEKELSHLNQEFETLQEKAQVNSRKAQTLYNNIDQT 1925
Q16787       1847 LQGLSaSAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRA 1926 human
Q00174       2134 LEDFNsVTLAFFTSQKLNY-YDQLADELEPKVKLLDPNSVDLSPSKKANSELESDAKSYAKQVNQTLANAFDIRERSSTT 2212 fruit fly
P19137       1582 VLSLN-LTGVSPAPYGILENLENTTKYFQRYLIKENAKKIRAEIQ---LEGIAEQTENLQKELTRVLARHQKVNAEMERT 1657 house mouse
P25391       1575 VLSLN-LTGIIPVPYGILSNLENTTKYLQESLLKENMQKDLGKIK---LEGVAEETDNLQKKLTRMLASTQKVNRATERI 1650 human
Q60675       1668 NSRAESLEEFIKGLVQDAEAINEKAVQLNEtlgnQDKTAERNLEELQKEIDRMLKELRSKD-LQTQKEVAEDELVAAEGL 1746 house mouse
Q16363        378 INHASQLVEQAHDMRDKIQEINNKMLYYGE----EHELSPKEISEKLVLAQKMLEEIRSRQpFFTQRELVDEEADEAYEL 453  human
O15230       2272 LGHAKTLLAAIRAVDRTLSELMSQTGHLGLa--nASAPSGEQLLRTLAEVERLLWEMRARD-LGAPQAAAEAELAAAQRL 2348 human
XP_017456642 1926 IQNAKELDMKIKNIIQNVHILLKQIARPGGe---GMDLPVGDWSRELAEAQRMLRELRGRD-FKKHLQEAEAQKMEAQLL 2001
Q16787       1927 TQSAKELDVKIKNVIRNVHILLKQISGTDGe---GNNVPSGDFSREWAEAQRMMRELRNRN-FGKHLREAEADKRESQLL 2002 human
Q00174       2213 LGNITVAYDEAVKSADQAKEAIASVEALSKn---LEAAASTKIDAALEQAQHILGQI---NgTSIELTPNEQVLEKARKL 2286 fruit fly
P19137       1658 SNGTQALATFIEQLHANIKEITEKVATLNQtarkDFQPPVSALQSMHQNISSLLGLIKERN-FTEMQQNATLELKAAKDL 1736 house mouse
P25391       1651 FKESQDLAIAIERLQMSITEIMEKT-TLNQtldeDFLLPNSTLQNMQQNGTSLLEIMQIRD-FTQLHQNATLELKAAEDL 1728 human
Q60675       1747 LKRVNKLfGEPRAQNEDMEKDLQQKLAEYKNKLDDAWDLLREATDKTRDANRLSAANQKNMTILETKKEAIEGSKRQIEN 1826 house mouse
Q16363        454 LSQAESW-QRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNM 532  human
O15230       2349 LARVQEQlSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQA 2428 human
XP_017456642 2002 LNRIRTWlESHQVENNGLLKNIRDSLNDYEAKLQDLRSVLQEAAAQGKQATGLNHENEGVLGAIQRQMKEMDSLKNDLTE 2081
Q16787       2003 LNRIRTWqKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTK 2082 human
Q00174       2287 YEEVNTLvLPIKAQNKSL-NALKNDIGEFSDHLEDLFNWSEASQAKSADVERRNVANQKAFD--NSKFDTVSEQKLQAEK 2363 fruit fly
P19137       1737 LSRIQKRfQKPQEKLKALKEA-NSLLSNHSEKLQAAEELLKEAGSKTQESNLLLLLVKANLKEFQEKKLRVQEEQNVTSE 1815 house mouse
P25391       1729 LSQIQENyQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHLLLMVNANLREFSDKKLHVQEEQNLTSE 1808 human
Q60675       1827 TLKEGNDILDEANRLLGEINSV 1848 house mouse
Q16363        533 SLSTSADSLTTPRLTLSELDDI 554  human
O15230       2429 TLHAARDTLASVFRLLHSLDQA 2450 human
XP_017456642 2082 HLATADASLLQTNSLLQRMDTS 2103
Q16787       2083 YLTTADSSLLQTNIALQLMEKS 2104 human
Q00174       2364 NIKDAGNFLINGDLTLNQINQK 2385 fruit fly
P19137       1816 LIAKGREWVDAAGTHTAAAQDT 1837 house mouse
P25391       1809 LIVQGRGLIDAAAAQTDAVQDA 1830 human
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