GEO DataSets

(Submitter supplied) Polyamines, crucial molecules involved in cell proliferation and growth, play a pivotal role in cancer development and progression. Within the tumor microenvironment, macrophages, key components of the immune system, exhibit a complex relationship with polyamines. Evidence suggests that polyamines can modulate macrophage polarization, influencing their functional phenotypes. Here, we detected the gene DNA methylation changes in spermine-stimulated human macrophages isolated from PBMCs and TAMs.

Organism:

Campylobacter jejuni; Francisella tularensis subsp. novicida; Yersinia pestis; Staphylococcus aureus; Mycobacterium avium subsp. paratuberculosis; Cowpox virus; Escherichia coli O157:H7; Francisella tularensis subsp. mediasiatica; Paslahepevirus balayani; Yersinia pseudotuberculosis; Rickettsia prowazekii; Bartonella quintana; Mycobacterium avium; Homo sapiens; Streptobacillus moniliformis; Bartonella henselae; Francisella tularensis subsp. tularensis; Francisella tularensis subsp. holarctica; Yersinia enterocolitica; Toxoplasma gondii; Salmonella enterica subsp. enterica serovar Typhimurium; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Leptospira interrogans; Rickettsia typhi; Mycobacterium tuberculosis variant bovis; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant microti; Mycobacterium canetti; Orthohantavirus seoulense

Type:

Methylation profiling by array

Platform:

GPL21445

4 Samples

Download data: IDAT, TXT

(Submitter supplied) In Mycobacterium tuberculosis, the PhoPR two-component regulatory system controls production and secretion of proteins and lipid virulence effectors. Several mutations, present in phoR of Mycobacterium canettii relative to M. tuberculosis, impact the expression of the PhoP regulon and the pathogenicity of the strains. Here, we analyse by RNA-seq the expression profile of PhoP-regulated genes between the two M. more...

Organism:

Mycobacterium canetti; Mycobacterium tuberculosis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL33344 GPL33345

12 Samples

Download data: TXT

(Submitter supplied) A microarray was developed to screen rodent samples for pathogens of zoonotic importance In the work described here, a homologue to Yersinia pestis was found in rodent samples after screening with the microarray

Organism:

Yersinia enterocolitica; Rickettsia prowazekii; Rickettsia typhi; Mycobacterium tuberculosis variant bovis; Toxoplasma gondii; Apodemus sylvaticus; Salmonella enterica subsp. enterica serovar Typhimurium; Campylobacter jejuni; Yersinia pestis; Mycobacterium tuberculosis variant microti; Rattus rattus; Mycobacterium canetti; Francisella tularensis subsp. mediasiatica; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Orthohantavirus seoulense; Bartonella quintana; Staphylococcus aureus; Mycobacterium avium; Rattus norvegicus; Cowpox virus; Escherichia coli O157:H7; Francisella tularensis subsp. holarctica; Leptospira interrogans; Francisella tularensis subsp. novicida; Yersinia pseudotuberculosis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Mus musculus; Streptobacillus moniliformis; Bartonella henselae; Francisella tularensis subsp. tularensis; Paslahepevirus balayani

Type:

Genome variation profiling by array

Platform:

GPL21445

65 Samples

Download data: TXT

(Submitter supplied) Oligonucleotides were purchased as 3′-amino-modified oligos from Metabion (Martinsried, Germany) and applied at a final concentration of 10 μM in Spotting Buffer 1 (Quantifoil Micro Tools, Jena, Germany). Arrays were spotted using a Microgrid II spotting machine (BioRobotics Inc., Cambridge, UK) according to the instructions of the manufacturer and assembled into ArrayStrips. Each oligonucleotide probe was replicated two-fold on the array. more...

Organism:

Leptospira interrogans; Campylobacter jejuni; Francisella tularensis subsp. novicida; Yersinia enterocolitica; Yersinia pestis; Yersinia pseudotuberculosis; Rickettsia prowazekii; Rickettsia typhi; Bartonella quintana; Staphylococcus aureus; Mycobacterium avium; Mycobacterium tuberculosis variant bovis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant microti; Toxoplasma gondii; Cowpox virus; Streptobacillus moniliformis; Bartonella henselae; Mycobacterium canetti; Escherichia coli O157:H7; Salmonella enterica subsp. enterica serovar Typhimurium; Francisella tularensis subsp. tularensis; Francisella tularensis subsp. holarctica; Francisella tularensis subsp. mediasiatica; Paslahepevirus balayani; Mammarenavirus choriomeningitidis; Orthohantavirus puumalaense; Orthohantavirus seoulense

2 Series

69 Samples

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