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Items: 1 to 20 of 275

1.

Dynamic regulation of miRNA accumulation during C. elegans larval development [smallRNA-Seq 1]

(Submitter supplied) Here, we profile miRNA expression at high temporal resolution (1 hr interval) from 18h to 33h at 25°C, during C. briggsae postembryonic development, which identifies several miRNAs with highly dynamic concentration changes
Organism:
Caenorhabditis briggsae
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21214
16 Samples
Download data: TXT
Series
Accession:
GSE245894
ID:
200245894
2.

Dynamic regulation of miRNA accumulation during C. elegans larval development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
4 related Platforms
226 Samples
Download data
Series
Accession:
GSE245904
ID:
200245904
3.

Caenorhabditis briggsae SDC-2 and DPY-27 ChIP-seq

(Submitter supplied) ChIP-seq for the SDC-2 and DPY-27 subunits of the dosage compensation complex in C. briggsae
Organism:
Caenorhabditis briggsae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL27110
10 Samples
Download data: BW
Series
Accession:
GSE214714
ID:
200214714
4.

Comparative analysis of piRNA sequences, targets and functions in Caenorhabditis nematodes

(Submitter supplied) Piwi proteins and Piwi-interacting RNAs (piRNAs) are best known for their roles in suppressing transposons and promoting fertility. Yet piRNA biogenesis and its mechanisms of action differ widely between distantly related species. To better understand the evolution of piRNAs, we characterized the piRNA pathway in C. briggsae, a sibling species of the model organism C. elegans. Our analyses define 25,883 piRNA producing-loci in C. more...
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL18245 GPL21214 GPL29990
12 Samples
Download data: FA
Series
Accession:
GSE203297
ID:
200203297
5.

Temperature-dependent small RNA expression depends on wild genetic backgrounds of Caenorhabditis briggsae

(Submitter supplied) Geographically distinct populations can adapt to the temperature conditions of their local environment, leading to temperature-dependent fitness differences between populations. Consistent with local adaptation, phylogeographically distinct Caenorhabditis briggsae nematodes show distinct fitness responses to temperature. The genetic mechanisms underlying local adaptation, however, remain unresolved. more...
Organism:
Caenorhabditis briggsae
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL21214
18 Samples
Download data: XLSX
Series
Accession:
GSE202589
ID:
200202589
6.

Large scale transposon co-option in the Caenorhabditis germline regulatory network

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
Platforms:
GPL31139 GPL18730
14 Samples
Download data: BW
Series
Accession:
GSE192540
ID:
200192540
7.

Large scale transposon co-option in the Caenorhabditis germline regulatory network [longCapSeq]

(Submitter supplied) The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that about one-third of C. elegans germline-specific promoters have been co-opted from CERP2 and CELE2 MITE elements and are regulated by HIM-17, a THAP domain-containing transcription factor related to a transposase. more...
Organism:
Caenorhabditis briggsae
Type:
Other
Platform:
GPL31139
4 Samples
Download data: BW
Series
Accession:
GSE192539
ID:
200192539
8.

Large scale transposon co-option in the Caenorhabditis germline regulatory network [ATAC-seq]

(Submitter supplied) The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that about one-third of C. elegans germline-specific promoters have been co-opted from CERP2 and CELE2 MITE elements and are regulated by HIM-17, a THAP domain-containing transcription factor related to a transposase. more...
Organism:
Caenorhabditis briggsae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL31139
4 Samples
Download data: BW
Series
Accession:
GSE192534
ID:
200192534
9.

Topoisomerases I and II facilitate the translocation of condensin DC in C. elegans

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing
Platforms:
GPL19757 GPL30947 GPL26672
147 Samples
Download data: BW, HIC, TAB
Series
Accession:
GSE188851
ID:
200188851
10.

Topoisomerases I and II facilitate the translocation of condensin DC in C. elegans [ChIP-seq]

(Submitter supplied) Condensin complexes are evolutionarily conserved molecular motors from the structural maintenance of chromosomes (SMC) family, that use ATPase activity to translocate along DNA and form loops. Condensin and topoisomerase II (TOP-2) are essential for the structure and function of mitotic chromosomes. While condensin-mediated DNA looping is thought to direct TOP-2 chain-passing activity to separate sister chromatids, it is not known if TOP-2 in turn regulates loop formation. more...
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL30947 GPL19757
87 Samples
Download data: BW
Series
Accession:
GSE188612
ID:
200188612
11.

Transcriptional Profiling of C. briggsae Temperate and Tropical representative strains after extreme cold

(Submitter supplied) Different populations of the same species survive different environments through local adaptation. Temperature is one of the most important driving forces that could result in local adaptation. Here, we studied the influence of extreme low temperature on the survival of two genetically and geographically distinct populations of the free-living Caenorhabditis briggsae. We found that Caenorhabditis briggsae strains of temperate origin had a cold resistant phenotype, while those originating from a tropical climate had reduced survival after cold treatment. more...
Organism:
Caenorhabditis briggsae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL29990
10 Samples
Download data: TXT
Series
Accession:
GSE171725
ID:
200171725
12.

Parental exposure to environmental stress results in evolutionarily conserved intergenerational changes in offspring gene expression

(Submitter supplied) These data demonstrate that parental exposure to bacterial infection and osmotic stress intergenerational changes in offspring gene expression in C. elegans, C. kamaaina, C. briggsae and C. tropicalis. Many of these intergenerational changes in gene expression are observed in multiple species and this data identified >250 genes that exhibit intergenerational changes in expression in all species tested.
Organism:
Caenorhabditis tropicalis; Caenorhabditis briggsae; Caenorhabditis elegans; Caenorhabditis kamaaina
Type:
Expression profiling by high throughput sequencing
4 related Platforms
105 Samples
Download data: TXT
Series
Accession:
GSE173987
ID:
200173987
13.

Genome-wide expression analysis of Caenorhabditis briggsae SPR-4/IVP-1 and HTZ-1/IVP-2 mutants

(Submitter supplied) The goal of this study is to identify differentially expressed genes in Cbr-spr-4(gu163)/Cbr-ivp-1(gu163) and Cbr-htz-1(gu167)/Cbr-ivp-2(gu167) mutant compare to AF16 wild-type (WT). Our study represents the first analysis of Cbr-spr-4/Cbr-ivp-1 and Cbr-htz-1/Cbr-ivp-2 transcriptomes in C. briggsae and facilitates investigations of Cbr-spr-4/Cbr-ivp-1 and Cbr-htz-1/Cbr-ivp-2 mediated processes 
Organism:
Caenorhabditis briggsae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16160
9 Samples
Download data: CSV, TAB
Series
Accession:
GSE133769
ID:
200133769
14.

Transcriptional profiling of Caenorhabditis elegans and Caenorhabditis briggsae before and after heat shock

(Submitter supplied) Transcriptional profiling of heat-shocked worms was compared to non-heat-shocked worms to determine genes that are induced upon heat shock in each species; heat-shock-induced genes in each species were compared
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL22765 GPL27110
12 Samples
Download data: TXT
Series
Accession:
GSE135987
ID:
200135987
15.

Analysis of Hybrid Incompatability between C nigoni and C briggsae by mRNA sequencing

(Submitter supplied) Two introgression strains (ZZY10307 and ZZY10330) of C. briggsae onto the X chromosome of C. nigoni results in male sterility. In order to determine the cause, we sequenced the mRNAs from young adult males from these two strains, and compared to fertile males of the two parent species (AF16 and JU1421). Two wild-type female samples were also included as platform QC.
Organism:
Caenorhabditis nigoni; Caenorhabditis briggsae
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21276 GPL21277
14 Samples
Download data: FASTA, TXT
Series
Accession:
GSE76306
ID:
200076306
16.

Analysis of Hybrid Incompatability between C nigoni and C briggsae

(Submitter supplied) An introgression of C. briggsae onto the X chromosome of C briggsae results in male sterility. In order to determine the cause, we sequenced small RNAs from this strain and compared to fertile males of the two parent species.
Organism:
Caenorhabditis nigoni; Caenorhabditis briggsae
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL21214 GPL21215
3 Samples
Download data: FA
Series
Accession:
GSE75763
ID:
200075763
17.

Developmental dynamics of C. elegans dosage compensation

(Submitter supplied) In Caenorhabditis elegans, the dosage compensation complex (DCC) specifically binds to and represses transcription from both X chromosomes in hermaphrodites. The DCC is composed of an X-specific condensin complex that interacts with several proteins. During embryogenesis, DCC starts localizing to the X chromosomes around the 40-cell stage, and is followed by X-enrichment of H4K20me1 between 100-cell to comma stage. more...
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13657 GPL13776 GPL20977
146 Samples
Download data: TXT
Series
Accession:
GSE67650
ID:
200067650
18.

Male and Female DNA and RNA sequencing in several nematode species

(Submitter supplied) The overall goal of this investigation was to investigate X-content of sex-biased genes in several nematode species. The following species of nematode were investigated: *C. elegans, *N2; *C. brenneri, *PB2801; *C. briggsae, *AF16; *C. remanei*, PB4641; *P. **pacificus, *PS312*.* Genomic DNA sequencing data was used to assign X and autosomal - linkage to unassembled sequencing contigs. Male and female RNA seq data was then generated and used to determine sex-biased expression. more...
Organism:
Caenorhabditis elegans; Pristionchus pacificus; Caenorhabditis briggsae; Caenorhabditis brenneri; Caenorhabditis remanei
Type:
Expression profiling by high throughput sequencing; Other
5 related Platforms
31 Samples
Download data: BEDGRAPH, FPKM_TRACKING
Series
Accession:
GSE53144
ID:
200053144
19.

Conservation of mRNA and protein expression during development of C. elegans

(Submitter supplied) Spatiotemporal control of gene expression is crucial for development and subject to evolutionary changes. Although proteins are the final product of most genes, the developmental proteome of an animal has not yet been comprehensively defined, and the correlation between RNA and protein abundance during development is largely unknown. Here, we globally measured and compared protein and mRNA expression changes during the life cycle of the nematodes C. more...
Organism:
Caenorhabditis elegans; Caenorhabditis briggsae
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18072 GPL13776
26 Samples
Download data: TXT
Series
Accession:
GSE53359
ID:
200053359
20.

Chromatin Immunoprecipitation of TRA-1 in C. elegans and C. briggsae

(Submitter supplied) The goal of this study is to identify and characterize sites in the C. elegans genome bound by the transcription factor TRA-1.
Organism:
Caenorhabditis briggsae; Caenorhabditis elegans
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL9269 GPL13657 GPL16160
19 Samples
Download data: BW
Series
Accession:
GSE48917
ID:
200048917
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