GEO DataSets

(Submitter supplied) Campylobacter jejuni produces a single flagellum on one or both poles of the cell, the polar flagella not only confer the bacterium darting motility but also involved in its virulence and metabolic processes. FlhF is a lately defined flagella biosynthesis regulator, but how it regulates flagella assembly isn’t clear at present. Previous research had indicated FlhF was associated with gene expression, to understanding its role in flagella system and its correlation with C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL22549

6 Samples

Download data: TXT

(Submitter supplied) Campylobacter jejuni is one of the most important causes of food-borne diseases in industrialized countries. It is known that amino acids are important nutrient source for this pathogen, because C. jejuni lacks enzymes related to glycolysis. However, the characteristics on metabolism of C. jejuni grown in the nutrient restricted medium with a specific amino acid is not fully elucidated. This study shows that C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni

Type:

Expression profiling by array

Platform:

GPL25530

2 Samples

Download data: TXT

(Submitter supplied) Bile plays an important role in digestion, absorption of fats, and the excretion of waste products, while concurrently providing a critical barrier against colonization by harmful bacteria. Previous studies have demonstrated that gut pathogens react to bile by adapting their protein synthesis. The ability of pathogens to respond to bile is remarkably complex and still incompletely understood. Here we show that Campylobacter jejuni, a leading bacterial cause of human diarrheal illness worldwide, responds to deoxycholate, a component of bile, by altering global gene transcription in a manner consistent with a strategy to mitigate exposure to reactive oxygen stress. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni subsp. jejuni F38011; Campylobacter jejuni subsp. jejuni 81-176

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL22649 GPL22651 GPL22650

14 Samples

Download data: TXT

(Submitter supplied) Objectives: The aim of the study was to investigate the Campylobacter jejuni response to subinhibitory concentrations of natural antimicrobial compound pinocembrin

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL19011

4 Samples

Download data: TXT

(Submitter supplied) This study investigates the CsrA regulon of the food-borne pathogen Campylobacter jejuni. Direct RNA binding targets of CsrA in two strains of C. jejuni, NCTC11168 and 81-176, were determined using RIP-seq.

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni subsp. jejuni 81-176

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL15730 GPL15729

4 Samples

Download data: WIG

(Submitter supplied) Objectives: The aim of the study was to characterize (-)-α-Pinene, which is one of the chemical constituents of Alpinia katsumadai seed essential oil responsible for its resistance modulatory activity in Campylobacter jejuni. Methods: Broth microdilution method was used to evaluate the antimicrobial and resistance modulatory potential of (-)-α-Pinene and ethidium bromide accumulation assay to determine its efflux-inhibitory activity in subinhibitory concentration. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL19011

4 Samples

Download data: GPR

(Submitter supplied) The gut of chicken is mostly colonised with Campylobacter jejuni and with 100 fold less C. coli. The competitive ability of C. coli OR12 over C. jejuni OR1 has been examined in experimental broiler chickens following the observation that C. coli replaced an established C. jejuni intestinal colonisation within commercial chicken flocks reared outdoors (El-Shibiny, A., Connerton, P.L., Connerton, I.F., 2005. more...

Organism:

Campylobacter coli; Campylobacter coli RM2228; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni RM1221; Campylobacter jejuni

Type:

Genome variation profiling by array

Platform:

GPL9022

6 Samples

Download data: TXT

(Submitter supplied) C. jejuni HPC5 is a Campylobacter strain isolated from chickens. Following bacteriophage CP34 treatment on chickens colonised by C. jejuni HPC5, a series of CP34 insensitive strains like C. jejuni HPC5 R14 and C. jejuni HPC5 R20 were obtained which compromised their ability to colonise chickens. Reintroduction of C. jejuni HPC5 R14 and R20 in to chickens led to reversion of these strains and the MRPs of the revertant strains fell in to different classes termed C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni; Campylobacter jejuni RM1221; Campylobacter coli RM2228

Type:

Expression profiling by array

Platform:

GPL9022

33 Samples

Download data: TXT

(Submitter supplied) C. coli is the predominant Campylobacter strain that is found in pigs while C. jejuni if present will be 10- 100 folds less. Natural transformation can occur if there is a coexistence of both the strains in the intestine of pigs. Genome analyses were performed on a C. jejuni strain U101 isolated from the upper intestine and two C. coli strains, C101 and L101 isolated from caecum and lower intestine.

Organism:

Campylobacter coli; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni; Campylobacter jejuni RM1221; Campylobacter coli RM2228

Type:

Genome variation profiling by array

Platform:

GPL9022

9 Samples

Download data: GPR, TXT

(Submitter supplied) During colonization in the host gastrointestinal tract, the enteric bacteria Campylobacter jejuni is exposed to a variety of signaling molecules including the catecholamine hormones epinephrine (Epi) and norepinephrine (NE). NE has been determined to stimulate the growth of C. jejuni as well as increase its pathogenicity. To investigate the mechanisms of NE or Epi on the biology of C. jejuni, the global gene expression profiles of C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL19679

10 Samples

Download data: TXT

(Submitter supplied) A number of six proteins were selected during immunoscreening and further analyses. The proteins were divided in silico into overlapping 15-mer oligopeptides with an overlap of 11 residues. The microarrays were incubated with different antibodies to K. pneumoniae, C. jejuni and S. aureus.

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Klebsiella pneumoniae

Type:

Protein profiling by protein array

Platforms:

GPL17961 GPL17960

20 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Campylobacter jejuni; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platforms:

GPL10622 GPL10196 GPL6687

10 Samples

Download data: TXT

(Submitter supplied) Erythromycin is the drug of choice to treat campylobacteriosis, but resistance to this antibiotic is rising. The adaptive mechanisms employed by Campylobacter jejuni to erythromycin treatment remain unknown. The aim of this study is to determine the molecular basis underlying Campylobacter’s immediate response to Ery treatment.

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni

Type:

Expression profiling by array

Platform:

GPL10622

3 Samples

Download data: TXT

(Submitter supplied) Erythromycin is the drug of choice to treat campylobacteriosis, but resistance to this antibiotic is rising. The adaptive mechanisms employed by Campylobacter jejuni to erythromycin treatment remain unknown. The aim of this study is to determine the molecular basis underlying Campylobacter’s immediate response to Ery treatment.

Organism:

Campylobacter jejuni; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL10196

3 Samples

Download data: TXT

(Submitter supplied) Campylobacter jejuni is a widespread pathogen responsible for most of the food-borne gastrointestinal diseases in Europe. For pathogen control in the food industry, the use of natural antimicrobial molecules is a promising strategy to avoid antibiotic treatments. Isothiocyanates are natural antimicrobial compounds which also display anti-cancer activity. Several studies described the chemoprotective effect of isothiocyanates on eukaryotic cells, but the antimicrobial mechanism is still poorly understood. more...

Organism:

Campylobacter jejuni; Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL6293

42 Samples

Download data: CSV

(Submitter supplied) We report the use of differential RNA-sequencing for the determination of the primary transcriptome of wildtype Campylobacter jejuni NCTC 11168. This allows for the genome-wide determination of transcription start sites.

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17504

2 Samples

Download data: GR

(Submitter supplied) Campylobacter, a major foodborne pathogen, is increasingly resistant to macrolide antibibotics. Previous findings suggested that development of macrolide resistance in Campylobacter requires a multi-step process, but the molecular mechanisms involved in the process are not known. In our study, erythromycin-resistant C. jejuni mutant (R) was selected in vitro by stepwise exposure of C. jejuni NCTC11168(S) to increasing concentrations of erythromycin.The resistant were subjected to microarray and the the global transcriptional profile was analyzed. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL17410

8 Samples

Download data: PAIR

(Submitter supplied) Cj0440c encodes a putative transcriptional regulator. To determine the role of Cj0440c in C.jejuni, we knocked out Cj0440c in the wild-type strain (S) to obtain the Cj0440c mutants (SM). Then we compared the transcriptome of the Cj0440c mutant with that of the parent strain using DNA microarray. These comparisons identified 19 genes that showed a≥2-fold change in expression in SM. The differentially expressed genes in SM encode proteins involved in flagellar biosynthesis, O-linked glycosylation and hypothetical proteins with unknown fuctions. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL17410

8 Samples

Download data: PAIR

(Submitter supplied) Cj0440c, a putative transcriptional regulator, was over-expressed in the high-level erythromycin-resistant (Eryr) Campylobacter jejuni strains. To determine the role of Cj0440c on the development and fitness of erythromycin resistance in C. jejuni, we knocked out Cj0440c in Eryr strain (R) to obtain the Cj0440c mutants (RM). Then we compared the transcriptome of the Cj0440c mutant with that of the parent strain using DNA microarray. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

Type:

Expression profiling by array

Platform:

GPL17410

8 Samples

Download data: PAIR

(Submitter supplied) Campylobacter jejuni is currently the leading cause of bacterial gastroenteritis in humans. Comparison of multiple Campylobacter strains revealed a high genetic and phenotypic diversity. However, little is known about differences in transcriptome organization, gene expression, and small RNA (sRNA) repertoires. Here we present the first comparative primary transcriptome analysis based on the differential RNA–seq (dRNA–seq) of four C. more...

Organism:

Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Campylobacter jejuni subsp. jejuni 81-176; Campylobacter jejuni subsp. jejuni 81116; Campylobacter jejuni RM1221

Type:

Expression profiling by high throughput sequencing

4 related Platforms

16 Samples

Download data: WIG