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| Status |
Public on Oct 10, 2013 |
| Title |
Transcriptional profiles of Campylobacter jejuni NCTC 11168 to 4mg/L erythromycin treatment |
| Platform organism |
Campylobacter jejuni |
| Sample organism |
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
| Experiment type |
Expression profiling by array
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| Summary |
Erythromycin is the drug of choice to treat campylobacteriosis, but resistance to this antibiotic is rising. The adaptive mechanisms employed by Campylobacter jejuni to erythromycin treatment remain unknown. The aim of this study is to determine the molecular basis underlying Campylobacter’s immediate response to Ery treatment.
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| Overall design |
The design utilized an available two color microarray slide for the entire transcriptome of Campylobacter jejuni wild type strain NCTC 11168. One hybridizations were performed: sham-treated NCTC 11168 v.s. lethal dose erythromycin treated NCTC 11168. Samples were independently grown and harvested. There were three biological replicates of each sample.
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| Contributor(s) |
Xia Q, Wu Z, Zhang Q |
| Citation(s) |
23767761 |
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| Submission date |
Dec 19, 2012 |
| Last update date |
Oct 10, 2013 |
| Contact name |
Qingqing Xia |
| E-mail(s) |
carole_xia@yahoo.com.cn
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| Organization name |
Iowa State University
|
| Street address |
1116 VMPM Iowa State University
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| City |
Ames |
| State/province |
IA |
| ZIP/Postal code |
50011 |
| Country |
USA |
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| Platforms (1) |
| GPL10196 |
JCVI PFGRC Campylobacter jejuni 15K v3 array designed primarily based on strain NCTC_11168 |
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| Samples (3) |
| GSM1055178 |
11168_treated with 4mg/L Erythromycin_replicate1 |
| GSM1055180 |
11168_treated with 4mg/L Erythromycin_replicate2 |
| GSM1055182 |
11168_treated with 4mg/L Erythromycin_replicate3 |
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| This SubSeries is part of SuperSeries: |
| GSE43026 |
Transcriptional profiles of Campylobacter jejuni NCTC 11168 and JL272 to erythromycin treatment |
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| Relations |
| BioProject |
PRJNA184069 |
