GEO DataSets

(Submitter supplied) Prokaryotic cell transcriptomics have been limited to mixed or sub-population dynamics and individuality of cells within heterogeneous populations. This significantly hampers further knowledge into spatiotemporal and stage-specific processes of prokaryotic cells within complex environments. Herein, we developed a ‘TRANSITomic’ approach to profile transcriptomes of single Burkholderia pseudomallei (Bp) cells as they transit through host cell infection at defined stages, yielding pathophysiological insights. more...

Organism:

Burkholderia pseudomallei; Burkholderia mallei

Type:

Expression profiling by array

Platform:

GPL29071

9 Samples

Download data: TXT

(Submitter supplied) As vector-borne pathogens transit between the arthropod and vertebrate, adaptation is key for survival as each host varies and initiates unique defense mechanisms. An environmental signal that relapsing fever (RF) and Lyme causing spirochetes detect is the change of temperature between vector and mammal, yet incomplete genomes have hindered progress in understanding the genetic constituents expressed during tick colonization. more...

Organism:

Coxiella burnetii; Rickettsia prowazekii; Francisella tularensis; Borrelia hermsii; Burkholderia mallei; Borrelia turicatae 91E135; Brucella suis

Type:

Expression profiling by array

Platform:

GPL7246

9 Samples

Download data: CEL, CHP

(Submitter supplied) The gene expression profiles were investigated and compared in spleen, lungs and liver of susceptible (BALB/c) and resistant (C57BL/6) hosts to identify genes participated in survival and virulence functions encoded in the B. pseudomallei genome. Subsequently, genes with unknown function and located with virulence gene clusters or suspected to be transcription regulator were selected for a novel virulence gene investigation

Organism:

Burkholderia mallei; Burkholderia pseudomallei; Burkholderia pseudomallei K96243

Type:

Expression profiling by array

Platform:

GPL17789

7 Samples

Download data: GPR

(Submitter supplied) Spirochetes are long, thin, motile, helical or flat wave bacteria that are unique among the prokaryotes by having flagella or axial filaments confined to an internal periplasmic space. These flagella are complex organelles that can play major roles in bacterial pathogenicity and are used as propellers allowing bacteria to move through liquids, viscous environments or along surfaces. While most bacteria species use transcriptional regulatory cascades to regulate the synthesis and assembly of their flagella, spirochetes employ an unusual post-transcriptional mechanism. more...

Organism:

Burkholderia mallei; Borrelia hermsii; Brucella suis; Francisella tularensis; Coxiella burnetii; Rickettsia prowazekii

Type:

Expression profiling by array

Platform:

GPL7246

24 Samples

Download data: CEL, CHP

(Submitter supplied) To use whole genome microarrays to compare the differences in genome contents of 5 B. pseudomallei isolated from clinical specimens and environmental sample with B. pseudomallei K96243 reference strain and reveals variable patterns of Genomic Islands (GIs) Keywords: Comparative genomic hybridization

Organism:

Burkholderia mallei; Burkholderia pseudomallei

Type:

Genome variation profiling by array

Platform:

GPL9800

5 Samples

Download data: GPR

(Submitter supplied) The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen, whose virulence requires proliferation inside host cells, including macrophages. Although some Francisella determinants of intracellular growth have been identified, much remains to be understood about the pathogenesis of this organism. In particular, how Francisella responds to its intracellular environment could provide clues about its intracellular biology and reveal pathogenic determinants based on their intracellular expression profiles. more...

Organism:

Borrelia hermsii; Burkholderia mallei; Francisella tularensis subsp. tularensis SCHU S4; Brucella suis; Francisella tularensis; Coxiella burnetii; Rickettsia prowazekii

Type:

Expression profiling by array

Platform:

GPL7246

32 Samples

Download data: CEL, CHP

(Submitter supplied) The array contains a total of 9,826 oligo probes (70-mer) consisting 5,174 oligos from B. mallei, 3,261 from B. pseudomallei 1710b and 1,391 from B. pseudomallei K96243 to which the design target belongs. These oligos correspond to a 100% sequence identity and 100% length hit with the locus given as the design target (more than one locus from different strains used in the design). Oligos are designed based on ORF sequence across all genomes for a given chip. more...

Organism:

Burkholderia mallei; Burkholderia pseudomallei

1 Series

9 Samples

Download data

(Submitter supplied) spotted ss-oligonucleotide (70 mers) Protocol: see manufacturer's website

Organism:

Burkholderia mallei; Burkholderia pseudomallei

1 Series

7 Samples

Download data

(Submitter supplied) The array contains a total of 9,826 oligo probes (70-mer) consisting 5,174 oligos from B. mallei, 3,261 from B. pseudomallei 1710b and 1,391 from B. pseudomallei K96243 to which the design target belongs. These oligos correspond to a 100% sequence identity and 100% length hit with the locus given as the design target (more than one locus from different strains used in the design). Oligos are designed based on ORF sequence across all genomes for a given chip. more...

Organism:

Burkholderia mallei; Burkholderia pseudomallei

1 Series

5 Samples

Download data

(Submitter supplied) custom pathogenic Affymetrix chip 2 manufactured for RML Protocol: standard Affymetrix protocol

Organism:

Borrelia hermsii; Francisella tularensis; Coxiella burnetii; Rickettsia prowazekii; Burkholderia mallei; Brucella suis

3 Series

65 Samples

Download data: CDF

(Submitter supplied) This set includes 9826 oligonucleotides, has 22176 spots distributed in 48 blocks. Protocol: 2QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei; Burkholderia pseudomallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 22176 spots distributed in 48 blocks. Protocol: 2QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei; Burkholderia pseudomallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 22176 spots distributed in 48 blocks. Protocol: 2QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei; Burkholderia pseudomallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 22176 spots distributed in 48 blocks. Protocol: 2QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei; Burkholderia pseudomallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 32448 spots distributed in 48 blocks. Protocol: QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 32448 spots distributed in 48 blocks. Protocol: QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 32448 spots distributed in 48 blocks. Protocol: QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei

Download data

(Submitter supplied) This set includes 9826 oligonucleotides, has 32448 spots distributed in 48 blocks. Protocol: QBM, with arrayer GENETIX, machine cycles 0, pen id 0, pen cycles 0, operator 0, humidity control 0, humidity set point0.000

Organism:

Burkholderia mallei

Download data