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Full record GDS4159

LNCap prostate cancer cell line response to loss of COnstitutive Photomorphogenic-1, ETV1 and c-JUN

Analysis of LNCap prostate cancer cells following siRNA-mediated knockdown of COP1, ETV1, and c-JUN. Ubiquitin ligase COP1 (RFWD2) negatively regulates the abundance of ETV1 and c-JUN, both of which have been linked to PC. Results provide insight into the role of COP1 as a tumor suppressor in PC.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 genotype/variation sets
Platform:
GPL570
Series:
GSE27914
15 Samples
Download data: CEL
DataSet
Accession:
GDS4159
ID:
4159

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