Similar studies for GEO DataSets (Select 992) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Links from GEO DataSets

Items: 18

Select item 9921.

Endoplasmic reticulum membrane-associated genes in breast cancer cell line MCF-7

Identification of genes whose mRNA are translated from the endoplasmic reticulum (ER) in the breast cancer cell line MCF-7. Secreted and membrane-bound proteins are preferentially translated in the ER. Results provide insight into the association of membrane-bound proteins and breast cancer.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL96
Series:: GSE1400
6 Samples

Download data: CEL

DataSet

Accession:: GDS992

ID:: 992

Select item 2000014002.

MCF-7 Fractionated RNA

(Submitter supplied) RNA from MCF-7 cells was fractionated by sucrose density gradient centrifugation to separate RNA associated with membrane-bound polysomes from RNA associated with free polysomes. These two populations were hybridized in triplicate to U133A microarrays. Keywords: repeat sample

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS992
Platform:: GPL96
6 Samples

Download data: CEL

Series

Accession:: GSE1400

ID:: 200001400

Select item 2000031803.

Yeast Membrane Bound Polysome

(Submitter supplied) Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. mRNA species bound to membrane-associated polysomes were separated from other mRNAs by sedimentation equilibrium or sedimentation velocity. The distribution of individual transcripts in the 'membrane-bound' and 'cytosolic' fractions was quantitated for thousands of genes by hybridization to DNA microarrays. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL2773
1 Sample

Download data

Series

Accession:: GSE3180

ID:: 200003180

Select item 2000000484.

Secreted and membrane-associated genes

(Submitter supplied) Large-scale identification of secreted and membrane-associated gene products using DNA microarrays. This study is described more fully in Diehn M et al.(2000) Nat Genet 25:58-62 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL179
1 Sample

Download data

Series

Accession:: GSE48

ID:: 200000048

Select item 2000040235.

Membrane-associated transcripts in Arabidopsis; their isolation...

(Submitter supplied) Membrane-associated, integral membrane and secreted proteins are of key importance in many cellular processes. For most of the 28 952 predicted proteins in Arabidopsis, the actual subcellular localisation has not been demonstrated experimentally. So far, their potential membrane-association has been deduced from algorithms that predict transmembrane domains and signal peptides. However, the comprehensiveness and accuracy of these algorithms is still limited. more...

Organism:: Arabidopsis thaliana

Type:: Expression profiling by array

Platform:: GPL3357
12 Samples

Download data

Series

Accession:: GSE4023

ID:: 200004023

Select item 2000061406.

Cross platform microarray analysis for robust identification of differentially expressed genes

(Submitter supplied) Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternative that is complementary to RT-PCR for identification of the more robust changes in gene expression profiles. In this paper, we combined statistical and functional analysis for the cross platform validation of two oligonucleotide-based technologies, Affymetrix (AFFX) and Applied Biosystems (ABI), and for the identification of differentially expressed genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL1426 GPL570
12 Samples

Download data: CEL

Series

Accession:: GSE6140

ID:: 200006140

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000038937.

Gene Expression Profiling of matched Ductal Carcinomas in Situ and Invasive Breast Tumors

(Submitter supplied) This is a matched-pair analysis of ductal carcinoma in situ (DCIS) and invasive component (IDC) of nine breast ductal carcinoma to identify novel molecular markers characterizing the transition from DCIS to IDC for a better understanding of its molecular biology. Keywords: Affymetrix-based Microarrays in Mamma carcinoma

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS2045 GDS2046
Platforms:: GPL570 GPL96
24 Samples

Download data

Series

Accession:: GSE3893

ID:: 200003893

Select item 20468.

Ductal carcinoma in situ to invasive ductal carcinoma progression (HG-U133 2.0)

Analysis of preinvasive ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) tumors. Pairs of patient-matched DCIS and IDC tumor specimens analyzed. Results provide insight into the mechanisms underlying the progression of DCIS to IDC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 7 individual sets

Platform:: GPL570
Series:: GSE3893
14 Samples

Download data

DataSet

Accession:: GDS2046

ID:: 2046

Select item 20459.

Ductal carcinoma in situ to invasive ductal carcinoma progression (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 5 individual sets

Platform:: GPL96
Series:: GSE3893
10 Samples

Download data

DataSet

Accession:: GDS2045

ID:: 2045

Select item 20000592710.

SNP expression data from breast cancer

(Submitter supplied) SNP Expression profiling of human breast cancer: 29 tumor samples, 4 pure normal breat samples and 8 lymphocytes samples Keywords: Human Cancer

Organism:: Homo sapiens

Type:: Genome variation profiling by SNP array

Platform:: GPL2005
41 Samples

Download data

Series

Accession:: GSE5927

ID:: 200005927

PubMed Similar studies

Select item 20000674611.

High-resolution genomic profiles of breast cancer cell lines

(Submitter supplied) A BAC-array platform for comparative genomic hybridization was constructed from a library of 32,433 clones providing complete genome coverage, and evaluated by screening for DNA copy number changes in 11 breast cell lines (BT474, MCF7, HCC1937, SK-BR-3, L56Br-C1, ZR-75-1, MCF10A, JIMT1, MDA-MB-231, MDA-MB-361 and HCC2218). These were also characterized by gene expression analysis and found to represent all five recently described breast cancer subtypes using the ‘intrinsic gene set’ and centroid correlation. more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL4723
11 Samples

Download data: TXT

Series

Accession:: GSE6746

ID:: 200006746

Select item 20001018112.

Genomic copy number alterations as predictive markers in breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
118 Samples

Download data: GPR

Series

Accession:: GSE10181

ID:: 200010181

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001012913.

Genomic copy number alterations as predictive markers of neoadjuvant chemotherapy response in breast cancer

(Submitter supplied) Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess different copy number changes between chemotherapy responsive and non-resposive breast cancer tissues. Keywords: Array CGH

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
56 Samples

Download data: GPR

Series

Accession:: GSE10129

ID:: 200010129

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001012814.

Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer

(Submitter supplied) Array CGH containing 4,044 human bacterial artificial chromosome clones was used to assess copy number changes in 31 pairs of clinicopathologically well matched recurred / nonrecurred breast cancer tissues. Keywords: array CGH

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array

Platform:: GPL5772
62 Samples

Download data: GPR

Series

Accession:: GSE10128

ID:: 200010128

Select item 20000222515.

Letrozole-, Anastrozole- and Tamoxifen-Responsive Genes in MCF-7aro Cells

(Submitter supplied) Anti-estrogens and aromatase inhibitors are important drugs in the treatment of estrogen-dependent breast cancer. In order to investigate the effects of these drugs on gene expression in breast cancer cells, we treated estrogen receptor-positive MCF-7 cells, stably transfected with the aromatase gene (known as MCF-7aro cells), with testosterone, 17β-estradiol, two aromatase inhibitors (letrozole and anastrozole), and an anti-estrogen (tamoxifen). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS1873
Platform:: GPL96
18 Samples

Download data: CEL, EXP

Series

Accession:: GSE2225

ID:: 200002225

Select item 187316.

Antiestrogen and aromatase inhibitor effect on breast cancer cells

Analysis of estrogen receptor positive, aromatase transfected MCF-7 cells after treatment with an antiestrogen (AE) or an aromatase inhibitor (AI). AEs and AIs are used to treat estrogen-dependent breast cancer. Cells also treated with androgen which is converted to estrogen by aromatase.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 6 agent, 4 other sets

Platform:: GPL96
Series:: GSE2225
18 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1873

ID:: 1873

Select item 20000274017.

Estrogen-regulated genes predict survival in estrogen receptor and/or progesterone receptor-positive breast cancers

(Submitter supplied) The prognosis of a patient with Estrogen Receptor (ER) and/or Progesterone Receptor (PR)-positive breast cancer is highly variable. Therefore, we developed a gene-expression based outcome predictor for ER+ and/or PR+ (i.e. Luminal) breast cancer patients using biological properties of the tumors. First, we identified estrogen-regulated genes using the ER+ MCF-7 breast cancer cell line treated with estrogen. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

4 related Platforms
174 Samples

Download data

Series

Accession:: GSE2740

ID:: 200002740

Select item 20000417518.

Genome-Scale Identification of Membrane-Associated Human mRNAs

(Submitter supplied) The subcellular localization of proteins is critical to their biological roles. Moreover, whether a protein is membrane-bound, secreted, or intracellular affects the usefulness of, and the strategies for, using a protein as a diagnostic marker or a target for therapy. We employed a rapid and efficient experimental approach to classify thousands of human gene products as either membrane-associated/secreted (MS) or cytosolic/nuclear (CN). more...