Similar studies for GEO DataSets (Select 4969) - GEO DataSets

Select item 49691.

CD138- and CD138+ MACS-sorted myeloma cell lines

Analysis of CD138+ and CD138− cells isolated from 8 multiple myeloma (MM) cell lines. The CD138- fraction is thought to represent MM stem cells. Results provide insight into the molecular bases of the CD138-/+ fractions of the MM cell lines.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 8 cell line, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE46816
16 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4969

ID:: 4969

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000468162.

Gene expression data from 8 pairs of CD138+/- myeloma cell lines

(Submitter supplied) 8 pairs of myeloma cell lines were sorted by MACS CD138-microbead, and the each cell lines were divided into two fraction CD138+ and CD138-. We used microarrays to detail the global programme of gene expression in these 8 pairs of CD138+/- myeloma cell lines

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4969
Platform:: GPL6244
16 Samples

Download data: CEL, CHP

Series

Accession:: GSE46816

ID:: 200046816

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000313053.

Expression data of myeloma CD138+ and CD138- populations

(Submitter supplied) Comparison of gene expression profiles between CD138+ and CD138- populations from human myeloma cell lines RPMI-8226 and NCI-H929. We used Affymetrix human gene 1.0ST array and analyzed with GeneSpring GX.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4970
Platform:: GPL6244
8 Samples

Download data: CEL

Series

Accession:: GSE31305

ID:: 200031305

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 49704.

CD138- and CD138+ FACS-sorted myeloma cell lines

Analysis of CD138+ and CD138− cells isolated from 2 multiple myeloma (MM) cell lines. The CD138- cells have greater clonogenic potential than the CD138+ plasma cells and exhibit stem cell properties. Results provide insight into the molecular basis of the CD138- clonogenic population.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell line, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE31305
8 Samples

Download data: CEL

DataSet

Accession:: GDS4970

ID:: 4970

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000330205.

CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype

(Submitter supplied) Although new therapies have doubled the survival of multiple myeloma (MM) patients, this remains an incurable disease. It has been postulated that the so-called MM Cancer Stem Cells (MM-CSC) would be responsible for tumor initiation and relapse but their unequivocal identification remains unclear. Here, we investigated in a panel of MM cell lines the presence of CD20+ cells harboring a MM-CSC phenotype. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
6 Samples

Download data: CEL

Series

Accession:: GSE33020

ID:: 200033020

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001096756.

Dual inhibition of EZH1/2 depletes stem cells and over-activates WNT signaling in multiple myeloma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL15520 GPL18573
8 Samples

Download data: BW, TXT

Series

Accession:: GSE109675

ID:: 200109675

PubMed Full text in PMC Similar studies

Select item 2001096747.

Dual inhibition of EZH1/2 depletes stem cells and over-activates WNT signaling in multiple myeloma [ChIP-seq]

(Submitter supplied) Multiple myeloma (MM) is a hematological malignancy caused by accumulation of abnormal clonal plasma cells. Despite the recent development of novel therapies, relapse of MM eventually occurs due to a remaining population of drug-resistant myeloma stem cells. Side population (SP) cells exhibit cancer stem cell-like characteristics in MM; thus targeting these cells is a promising strategy to completely cure this malignancy. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL15520
4 Samples

Download data: BW

Series

Accession:: GSE109674

ID:: 200109674

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001096738.

Dual inhibition of EZH1/2 depletes stem cells and over-activates WNT signaling in multiple myeloma [RNA-seq]

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
4 Samples

Download data: TXT

Series

Accession:: GSE109673

ID:: 200109673

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000026589.

Gene Expression Profiles of Multiple Myeloma

(Submitter supplied) Samples in this series are pre-treatment bone marrow aspirates from multiple myeloma patients. Keywords = Multiple Myeloma, Bone Marrow, Pre-Treatment Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
559 Samples

Download data

Series

Accession:: GSE2658

ID:: 200002658

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005875110.

Genes regulated by SDC1 in Caco-2 cells

(Submitter supplied) We used Affymetrix HG U133 Plus 2.0 GeneChips to compare the transcriptome of Caco-2 cells transfected with SDC1-siRNA against negative control siRNA-transfected cells.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE58751

ID:: 200058751

Select item 20004458111.

Hedgehog pathway inhibition in chondrosarcoma using the Smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth

(Submitter supplied) Mice bearing primary human chondrosarcoma xenografts were treated with IPI 926, and mRNA levels of known Hh pathway genes and endpoint tumor volumes were measured. Gene expression profiling of IPI-926 treated tumors was conducted to identify potential novel Hh target genes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
8 Samples

Download data: TXT

Series

Accession:: GSE44581

ID:: 200044581

Select item 20000075512.

MRI lytic and no lytic lesions

(Submitter supplied) This series represents samples of multiple myeloma patients with and without bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS531
Platform:: GPL8300
173 Samples

Download data

Series

Accession:: GSE755

ID:: 200000755

Select item 20000075413.

MRI-lytic-lesion

(Submitter supplied) This series represents samples of multiple myeloma patients with bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
137 Samples

Download data

Series

Accession:: GSE754

ID:: 200000754

Select item 20000075314.

MRI-no-lytic-lesion

(Submitter supplied) This series represents samples of multiple myeloma patients without bone lytic lesion by MRI. Keywords = multiple myeloma Keywords = osteolytic lesions Keywords = MRI Keywords = osteoblast Keywords = mesenchymal stem cell Keywords = Wnt signaling Keywords = DKK1 Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
36 Samples

Download data

Series

Accession:: GSE753

ID:: 200000753

Select item 53115.

Multiple myeloma and bone lesions

Comparison of gene expression in bone marrow plasma cells of multiple myeloma patients with and without bone lesions. Osteolytic lesions increase in multiple myeloma patients.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL8300
Series:: GSE755
173 Samples

Download data

DataSet

Accession:: GDS531

ID:: 531

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