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Links from GEO DataSets

Items: 20

1.
Full record GDS401

Spermatogenesis time course (MG-U74A)

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 age, 3 tissue sets
Platform:
GPL81
Series:
GSE640
17 Samples
Download data: CEL
2.

Spermatogenesis

(Submitter supplied) A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets. Understanding mammalian spermatozoan development and the events surrounding fertilization has grown slowly, in part because of uncertainty about the number and identity of the cellular components involved. Determination of those transcripts expressed specifically by germ cells should provide an inclusive list of probable critical proteins. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS401 GDS409 GDS410
Platforms:
GPL82 GPL83 GPL81
51 Samples
Download data: CEL
Series
Accession:
GSE640
ID:
200000640
3.
Full record GDS410

Spermatogenesis time course (MG-U74C)

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 age, 3 tissue sets
Platform:
GPL83
Series:
GSE640
17 Samples
Download data: CEL
4.
Full record GDS409

Spermatogenesis time course (MG-U74B)

Analysis of C57BL/6 testis from day 1 to adult. Determination of transcripts expressed specifically by male germ cells late in spermatogenesis (postmeiotic) reveals many candidates for contraceptive targeting and fertilization participants.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 11 age, 3 tissue sets
Platform:
GPL82
Series:
GSE640
17 Samples
Download data: CEL
5.

Riding the spermatogenic wave: Profiling gene expression within neonatal germ and Sertoli cells during a synchronized initial wave of spermatogenesis

(Submitter supplied) WIN 18,446/RA treatment of neonatal mice was used to synchronize the initial wave of spermatogenesis and identify novel messages expressed within either germ or Sertoli cells as spermatogonia enter meiosis.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
77 Samples
Download data: CEL
Series
Accession:
GSE54408
ID:
200054408
6.

High-Resolution Profiling of Novel Transcribed Regions During Rat Spermatogenesis

(Submitter supplied) Mammalian spermatogenesis is a complex and highly orchestrated combination of processes in which male germline proliferation and differentiation result in the production of mature spermatozoa. If recent genome-wide studies have contributed to the in-depth analysis of the male germline protein-coding transcriptome, little effort has yet been devoted to the systematic identification of novel unannotated transcribed regions expressed during mammalian spermatogenesis. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL10287
8 Samples
Download data: BED, GTF, TXT
Series
Accession:
GSE48321
ID:
200048321
7.

Expression profiling of rainbow trout testicular development and spermatogenesis

(Submitter supplied) Trout spermatogenesis proceeds seasonally in a way that all morphological and cellular events tend to be synchronized. We thus used gonads at key stages of the male reproductive cycle together with isolated germ cell populations to study the changes in gene expression underlying testis development. Statistical analysis followed by clustering of expression profiles allowed the discrimination of sequential events of gene activation or repression during testis development and/or throughout the germline.
Organism:
Oncorhynchus mykiss
Type:
Expression profiling by array
Platform:
GPL3650
38 Samples
Download data: QTF
Series
Accession:
GSE16029
ID:
200016029
8.

Round Spermatids and Pachytene Spermatocytes

(Submitter supplied) Mouse Round Spermatids (Sptd) and Pachytene Spermatocytes (Spcy) Keywords: repeat sample
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1451 GPL1452 GPL1450
9 Samples
Download data
Series
Accession:
GSE1768
ID:
200001768
9.

Ctnnb1-targeted genes in mouse post-meiotic germ cells

(Submitter supplied) To determine differential gene expression in Ctnnb1 CKO mice testis compared to CTRL mice testis.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL4134
2 Samples
Download data: TXT
Series
Accession:
GSE30773
ID:
200030773
10.

Small RNA and mRNA transcriptome profiling in wildtype mice at multiple stages of spermatogenesis, from whole testis at day 1 postpartum (pp), day 3 pp, and day 7 pp and purified leptotene/zygotene and pachytene spermatocytes.

(Submitter supplied) MicroRNAs are essential for spermatogenesis. However, the stage‑specific requirements for specific miRNAs in the male mammalian germ line remain largely uncharacterized. The miR‑34 family is, to date, the only miRNA proven to be necessary for the production of sperm in mice, though its germline roles are poorly understood. Here, we generate and analyze paired small RNA and mRNA profiles across different stages of germline development in male mice, focusing on time points shortly before and during meiotic prophase I.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL17021 GPL13112
20 Samples
Download data: TXT
Series
Accession:
GSE83264
ID:
200083264
11.

Developmental changes in RNP and Polysome associated mRNAs in Mouse testes

(Submitter supplied) Gametes rely heavily on post-transcriptional control mechanisms to regulate their differentiation. In eggs, the storage and selective temporal activation of maternal mRNAs is essential for normal development. In the male, transcription ceases during spermiogenesis necessitating the post-transcriptional regulation of many paternal mRNAs required for spermatid differentiation and spermatozoan function. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2277
Platform:
GPL339
18 Samples
Download data: CEL
Series
Accession:
GSE4711
ID:
200004711
12.
Full record GDS2277

Ribonucleoprotein- and polysome-associated mRNAs of the testis: time-course

Analysis of ribonucleoprotein (RNP) and polysome fractions of prepuberal and adult testes. Protein synthesis occurs on polysomes and translationally inactive mRNAs are sequestered as RNPs. Results provide insight into the translation state of individual mRNAs as spermatogenesis proceeds.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 development stage, 2 other sets
Platform:
GPL339
Series:
GSE4711
18 Samples
Download data: CEL
13.

Topaz1, a germ cell specific factor essential for male meiotic progression.

(Submitter supplied) Testicular gene expression changes with loss of Topaz1
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
12 Samples
Download data: TXT
Series
Accession:
GSE67229
ID:
200067229
14.

miRNA-mRNA networks in mouse testis during the 1st wave of spermatogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platforms:
GPL6246 GPL16219
15 Samples
Download data: CEL, TXT
Series
Accession:
GSE41859
ID:
200041859
15.

Microarray profiling of total testicular transcriptome in mouse

(Submitter supplied) Gene expression during spermatogenesis is highly variable and this differential pattern is very important for the successive culmination of different stages of the process, leading to production of the male gamete. Taking the time window of first wave of spermatogenesis, we did a microarray profiling of total testicular transcriptome in mouse and found several significant patterns of variable gene expression, forming upregulated and downregulated clusters among the three stages analyzed here.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
9 Samples
Download data: CEL
Series
Accession:
GSE41858
ID:
200041858
16.

Microarray profiling of total testicular microRNAs in mouse

(Submitter supplied) Gene expression in mammalian testis undergoing spermatogenesis is under strict post transcriptional regulation and microRNAs are known to play a role in this regulation. Considering the time window of first wave of spermatogenesis, we did a microarray profiling of total testicular microRNAs in mouse and found several significant patterns of variable expression of these molecules during the different stages analyzed here.
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL16219
6 Samples
Download data: TXT
Series
Accession:
GSE41857
ID:
200041857
17.

Drosophila melanogaster spermatogenesis expression profile: mitotic, meiotic and post-meiotic cells

(Submitter supplied) We conducted a genome-wide expression analysis of wild-type males using three cell populations isolated from mitotic, meiotic and post-meiotic phases of spermatogenesis in Drosophila melanogaster. Our approach was to directly isolate testis regions enriched with RNAs from each of the three specific germline phases. We used microarrays to detail the global gene expression profile in spermatogenesis and identified up- and down-regulated genes between two different spermatogenic phases in pairwise comparisons
Organism:
Drosophila melanogaster
Type:
Expression profiling by array
Platform:
GPL1322
9 Samples
Download data: CEL
Series
Accession:
GSE18502
ID:
200018502
18.

Transcriptomic sequencing of the murine testis during the first wave of spermatogenesis

(Submitter supplied) Our experimental design includes samples at different time points during the first wave of spermatogenesis. Each time point corresponds to specific cell content in the testis. First time point is post natal day (PND) 7, when only somatic cells and spermatogonia are present in the testis. Thereafter additional cell types are present in selected samples in chronological order: PND 14 contains early spermatocytes, PND 17 late spermatocytes, PND 21 round spermatids and finally PND 28 elongating spermatids. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL14602
12 Samples
Download data: TAB
Series
Accession:
GSE39970
ID:
200039970
19.

Translational activation of developmental mRNAs during neonatal mouse testis development

(Submitter supplied) The sequence of gene regulatory events that drive neonatal germ cell development in the mammalian testis is not yet clear. We assessed changes in mRNA utilization in the neonatal testis at 1 and 4 dpp, times when the testis contains quiescent gonocytes (1 dpp) and proliferating spermatogonia (4 dpp). There are not thought to be major changes in the nature or number of somatic cells over that interval. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
12 Samples
Download data: CEL
Series
Accession:
GSE49283
ID:
200049283
20.

Arraystar lncRNA and mRNA microarray data for profiling of testis-specific long noncoding RNA in mice

(Submitter supplied) LncRNA and mRNA expression profiles in five mouse tissues like brain, heart, kidney, liver and testis and three germ cell-related cell lines such as F9, GC-1 and GC-2
Organism:
Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL24126
24 Samples
Download data: TXT
Series
Accession:
GSE105024
ID:
200105024
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