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Links from GEO DataSets

Items: 2

1.
Full record GDS3766

Inhibitor of nuclear factor kappa B kinase beta-subunit overactivity effect on skin cells

Analysis of back skin from transgenic (Tg) animals with keratinocyte-specific IKKbeta overexpression. The Tg animals present an inflammatory skin phenotype with histological features characteristic of interface dermatitis. Results provide insight into the role of IKKbeta in skin physiopathology.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE17511
4 Samples
Download data: CEL
DataSet
Accession:
GDS3766
ID:
3766
2.

Expression data from K5-IKKbeta transgenic mouse skin

(Submitter supplied) IKKbeta is a subunit of the IkB kinase (IKK) complex required for NF-kB activation in response to pro-inflammatory signals. NF-kB regulates the expression of many genes involved in inflammation, immunity and apoptosis, and also controls cell proliferation and differentiation in different tissues; however, its function in skin physiopathology remains controversial. We here report the alterations caused by increased IKKbeta activity in basal cells of the skin of transgenic mice.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3766
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE17511
ID:
200017511

Supplemental Content

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