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Links from GEO DataSets

Items: 20

1.
Full record GDS2804

Quiescent stb3 null mutant response to glucose

Analysis of the response of quiescent stb3 null cells to glucose. STB3 encodes a protein that binds to the Ribosomal RNA Processing Element, a DNA sequence motif that regulates genes needed for growth. Results provide insight into Stb3’s role during the transition from quiescence to rapid growth.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 growth protocol sets
Platform:
GPL90
Series:
GSE8379
8 Samples
Download data: CEL
DataSet
Accession:
GDS2804
ID:
2804
2.

Stb3 deletion affects gene expression within 10 minutes of glucose addition

(Submitter supplied) Microarrays were conducted to asses the effect of Stb3 deletion in immediate transcriptional induction in response to glucose Keywords: Stb3, immediate glucose induction, growth genes.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Dataset:
GDS2804
Platform:
GPL90
8 Samples
Download data: CEL
Series
Accession:
GSE8379
ID:
200008379
3.

aerobic_to_anaerobic_shift

(Submitter supplied) The wild-type (grown on galactose or glucose) or msn2/4 mutant (grown on galactose) strains were grown aerobically. At time zero (generation 0) the sparge gas was switched from air to O2-free N2 and samples were harvested after 0 (aerobic control), 0.04, 0.08, 0.19, and 2 generations of anaerobic growth. Keywords: time-course
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Datasets:
GDS2002 GDS2003
Platform:
GPL1535
45 Samples
Download data
Series
Accession:
GSE1879
ID:
200001879
4.
Full record GDS2003

Msn2/4 role in metabolic remodeling during short-term anaerobiosis: time course

Analysis of catabolite-derepressed (galactose) wildtype JM43 and isogenic msn2/4 mutant KKY8 cells shifted to short-term anaerobiosis (2 generations). Msn2 and 4 are key stress factors. Results suggest Msn2/4 involvement in metabolic remodeling during acclimatization to short-term anaerobiosis.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, log2 ratio, 2 genotype/variation, 2 protocol, 5 time sets
Platform:
GPL1535
Series:
GSE1879
30 Samples
Download data
5.
Full record GDS2002

Metabolic state-dependent stress response to short-term anaerobiosis: time course

Analysis of catabolite-repressed (glucose) or derepressed (galactose) wildtype JM43 cells shifted from aerobiosis to anaerobiosis (2 generations). Results identify metabolic remodeling that occurs during acclimatization to short-term anaerobiosis in galactose but not in glucose.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, log2 ratio, 2 growth protocol, 2 protocol, 5 time sets
Platform:
GPL1535
Series:
GSE1879
30 Samples
Download data
6.

Time-course gene expression profiles of a Saccharomyces cerevisiae wild type and long-lived sch9-delta mutant

(Submitter supplied) The SCH9 null strain has smaller cell size, grows at a slower rate and survives three times longer than wide-type yeast. This study aims to dissect the mechanisms that lead to the yeast life span extension of sch9-delta.
Organism:
Saccharomyces cerevisiae; Schizosaccharomyces pombe
Type:
Expression profiling by array
Platform:
GPL2529
19 Samples
Download data: CEL
Series
Accession:
GSE14227
ID:
200014227
7.

Genome-wide location analysis of Abf1 and Reb1 in Saccharomyces cerevisiae

(Submitter supplied) Abf1 and Reb1, two general regulatory factors playing roles at promoters and other genome functional sites in budding yeast, were mapped genome-wide by ChIP-sequencing using strains expressing TAP-tagged versions of the proteins. As expected on the basis of previous in silico analysis of promoter regions, we found that these factors are enriched at the promoters of ribosome biogenesis (Ribi) genes, a large regulon of more than 200 genes required for ribosome biosynthesis and assembly, and known to be coordinately regulated in response to nutrient availability and cellular growth rate.
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17342
4 Samples
Download data: BED
Series
Accession:
GSE81112
ID:
200081112
8.

Mechanisms Coordinating Ribosomal Protein Gene Transcription in Response to Stress

(Submitter supplied) In this study, we elucidate the common logic of the RPGs regulatory network by evaluating both the architecture and activity of promoters under conditions of stress or modulation of TF levels, and we identified the proteins regulating the activity of promoters lacking Rap1 binding, thus demonstrating that RPG co-regulation requires the complementary action of two different mechanisms involving both Ifh1 and Sfp1.
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platform:
GPL17342
22 Samples
Download data: BIGWIG, BW
Series
Accession:
GSE155235
ID:
200155235
9.

Genome-wide binding of Fhl1 and Ifh1 +/- Rapamycin

(Submitter supplied) Array design -Platform: amino-silane coated glass slides (GAPS II, Corning) -S. cerevisiae intergenic regions amplified from S288C genomic DNA (ResGen) using the intergenic region primer oligonucleotides (ResGen) (Harismendy et al. EMBO J. 22(18): 4738-4747, 2003). The primers allow the amplification of the sequence located on either side of elements such as open reading frames, tRNAs, small nuclear RNAs, Ty elements, solo δ, etc. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL1695
15 Samples
Download data: TIFF
Series
Accession:
GSE1944
ID:
200001944
10.

Time course of glycine addition or withdrawal

(Submitter supplied) +Gly 20, 40, 80: Cells were grown to early log phase (OD600 ~ 0.2) at 30oC in 1 liter of minimal B medium (Cherest, H., and Surdin-Kerjan, Y. (1992) Genetics 130, 51-58) and t=0 time point samples were harvested (250 ml). The remainder of the medium was supplemented with 10 mM glycine incubated at 30oC and samples (250 ml) harvested at 20, 40 and 80 minutes. All cells were harvested by rapid centrifugation at room temperature then flash frozen in liquid nitrogen. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platforms:
GPL1336 GPL1337
20 Samples
Download data
Series
Accession:
GSE1554
ID:
200001554
11.

Steady state +/- Gly

(Submitter supplied) Cells were grown to early log phase (OD600 ~ 0.2) at 30oC in 1 liter of minimal B medium (Cherest, H., and Surdin-Kerjan, Y. (1992) Genetics 130, 51-58) with or without supplementation with 10 mM glycine and harvested. All cells were harvested by rapid centrifugation at room temperature then flash frozen in liquid nitrogen. Arrays compared expression of Gly- cells to the Gly+ controls. Strain BY4741 was the wild type and several deletion strains were also used. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL1336
8 Samples
Download data
Series
Accession:
GSE1553
ID:
200001553
12.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13272
25 Samples
Download data: BAM, BIGWIG
Series
Accession:
GSE29125
ID:
200029125
13.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (ChIP-Seq data)

(Submitter supplied) TORC1 is a structurally and functionally conserved multiprotein complex that regulates many aspects of eukaryote growth including the synthesis and assembly of ribosomes. The protein kinase activity of this complex is responsive to environmental cues and is potently inhibited by the natural product macrolide rapamycin. Insights into how TORC1 regulates growth have been provided with the recent identification of the rapamycin-sensitive phosphoproteome in yeast. more...
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL13272
9 Samples
Download data: BAM, BIGWIG
Series
Accession:
GSE29124
ID:
200029124
14.

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (mRNA-Seq data)

(Submitter supplied) TORC1 is a structurally and functionally conserved multiprotein complex that regulates many aspects of eukaryote growth including the synthesis and assembly of ribosomes. The protein kinase activity of this complex is responsive to environmental cues and is potently inhibited by the natural product macrolide rapamycin. Insights into how TORC1 regulates growth have been provided with the recent identification of the rapamycin-sensitive phosphoproteome in yeast. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13272
16 Samples
Download data: BAM
Series
Accession:
GSE29122
ID:
200029122
15.

Fhl1 and lfh1 ChIP-chip

(Submitter supplied) Fhl1-9myc ChIP-chip, YPD, OD600=0.8, 2 arrays with duplicate spotting of yeast intergenic regions. AND Ifh1-9myc ChIP-chip, cells grown in YPD, OD600=0.8, 2 arrays with duplicate spotting of yeast intergenic regions. Keywords = Fhl1 Keywords: other
Organism:
Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by array
Platform:
GPL1689
8 Samples
Download data
Series
Accession:
GSE1930
ID:
200001930
16.

BY_wild_parents

(Submitter supplied) Expression analysis of BY4716(isogenic to S288c) and a wild isolate collected by R. Mortimer. Each strain was grown in culture 6 independent times and RNA from each culture was isolated. Each of these RNA samples was subjected to a dye-swap pair of arrays (except the "RM11" sample, which only got one array). All arrays used the same pool of reference BY4716 sample. In sample titles, "BY" alone signifies the reference sample and all other strings represent independent cultures. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Datasets:
GDS93 GDS94
Platform:
GPL118
23 Samples
Download data
Series
Accession:
GSE38
ID:
200000038
17.

BYxwild_40

(Submitter supplied) Expression analysis of F1 haploid segregants from a cross between BY4716 (isogenic to S288c) and a wild isolate collected by R. Mortimer. Each segregant sample was subjected to a dye-swap pair of arrays. All arrays used the same pool of reference BY4716 sample. In sample titles, "BY" alone signifies the reference sample and all other strings represent segregants. All sample titles are of the form S1-S2. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Datasets:
GDS91 GDS92
Platform:
GPL118
80 Samples
Download data
Series
Accession:
GSE37
ID:
200000037
18.
Full record GDS94

Transcriptional regulation (II)(dye-swap)

Genetic linkage analysis of global expression levels in a cross between two budding yeast strains. Identification of cis-acting and trans-acting loci that modulate a total of 570 genes.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, log ratio, 2 strain sets
Platform:
GPL118
Series:
GSE38
11 Samples
Download data
DataSet
Accession:
GDS94
ID:
94
19.
Full record GDS93

Transcriptional regulation (II)

Genetic linkage analysis of global expression levels in a cross between two budding yeast strains. Identification of cis-acting and trans-acting loci that modulate a total of 570 genes.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, log ratio, 2 strain sets
Platform:
GPL118
Series:
GSE38
12 Samples
Download data
DataSet
Accession:
GDS93
ID:
93
20.
Full record GDS92

Transcriptional regulation (I)(dye-swap)

Genetic linkage analysis of global expression levels in a cross between two budding yeast strains. Identification of cis-acting and trans-acting loci that modulate a total of 570 genes.
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array, log ratio, 7 other sets
Platform:
GPL118
Series:
GSE37
40 Samples
Download data
DataSet
Accession:
GDS92
ID:
92
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