Similar studies for GEO DataSets (Select 2230) - GEO DataSets

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Items: 12

Select item 22301.

Intestinal absorptive cell model response to iron deficiency and overload

Analysis of intestinal CaCo-2 cell line grown in medium free of iron or supplemented with hemin to mimic iron overload. Intestinal iron absorption is crucial for systemic iron homeostasis. Results provide insight into molecular mechanisms regulating iron metabolism.

Organism:: Homo sapiens

Type:: Expression profiling by array, log10 ratio, 4 agent, 2 growth protocol sets

Platform:: GPL887
Series:: GSE3573
12 Samples

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DataSet

Accession:: GDS2230

ID:: 2230

Select item 2000035732.

Transcriptional effect of various iron treatments on Caco-2 cells.

(Submitter supplied) We investigated transcriptional response of CaCo-2 cells to iron treatments, we studied hemin effect by adding hemin to DMEM-FBS medium and iron deficiency effects in using an iron free medium compared to the same supplemented with FAC (ferric ammonium citrate). Keywords: various iron treatment, differential gene expression, hemin treatment, iron-free

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2230
Platform:: GPL887
12 Samples

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Series

Accession:: GSE3573

ID:: 200003573

Select item 2000070703.

Gene expression profiles of Chlamydophila pneumoniae during the acute and iron mediated persistent infection

(Submitter supplied) The obligate intracellular, gram-negative bacterium, Chlamydophila pneumoniae (Cpn), has impact as an acute and chronic disease-causing pathogen. Little is known about changes in the Cpn transcriptome during its biphasic developmental cycle (the acute infection) and persistence stages that are linked to chronic diseases. To analyze Cpn CWL029 gene expression, we designed a pathogen-specific oligo microarray and optimized the extraction method for pathogen RNA. more...

Organism:: Chlamydia pneumoniae

Type:: Expression profiling by array

Platform:: GPL4824
67 Samples

Download data: TXT, XML

Series

Accession:: GSE7070

ID:: 200007070

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000033124.

Expression Changes Relevant for Apoptosis in K562 Cells Co-Treated with Amifostine and Imatinib

(Submitter supplied) We had previously demonstrated an increased proapoptotic effect of Imatinib (STI571) in combination with Amifostine (AMI) in K562 cell line. In this study we used genomic scale gene expression profiling to monitor changes at transcriptional level in K562 cells during the treatment with AMI+STI571. We identified a transcriptional repressor of survival genes, known as BTF, which triggers a pro-apoptotic signal, potentially helpful to overcome the resistance to STI571. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
4 Samples

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Series

Accession:: GSE3312

ID:: 200003312

Select item 2000032945.

Comparative study of gene expression in human colorectal cancer tissues and normal mucosa

(Submitter supplied) The purpose of our study was to better understand the genetic mechanism of oncogenesis for human colorectal cancer and to identify potential new tumour markers of use in clinical practice. Results: Comparing cancerous tissues with normal colonic mucosa we identified 584 known genes (3%) differentially expressed to a significant degree (p<0.001). Many of the transcripts that were more abundant in tumours than in non-neoplastic tissues appear to reflect important events for colon carcinogenesis. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2829
24 Samples

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Series

Accession:: GSE3294

ID:: 200003294

Select item 2000057986.

In vivo gene expression in granulosa cells during pig terminal follicular development.

(Submitter supplied) The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and small versus medium follicles) and a pig multi-tissue cDNA library. Granulosa cells were isolated from healthy follicles (small, medium or large), 24 h or 96 h after the end of a progestagen treatment. more...

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL3978
46 Samples

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Series

Accession:: GSE5798

ID:: 200005798

Select item 2000057977.

In vivo gene expression in granulosa cells during pig terminal follicular development- oligo

(Submitter supplied) These vector oligonucleotide hybridizations were performed to determine the quality of the spotting process. EST with low signal values of the vector array were excluded from the analysis, since they probably were mis-amplified or mis-spotted Keywords: spotting control

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL3978
4 Samples

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Series

Accession:: GSE5797

ID:: 200005797

Select item 2000107488.

Expression data from brain tissue of Rattus norvegicus treated with D-Serine

(Submitter supplied) d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxicity) in brain tissue. The transcriptomic changes that occur in the brain after d-serine exposure have not been fully explored. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3643
Platform:: GPL1355
24 Samples

Download data: CEL

Series

Accession:: GSE10748

ID:: 200010748

Select item 36439.

D-serine effect on the brain: dose response

Analysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent, 6 dose sets

Platform:: GPL1355
Series:: GSE10748
24 Samples

Download data: CEL

DataSet

Accession:: GDS3643

ID:: 3643

Select item 20000782110.

Expression data from human intestinal biopsies

(Submitter supplied) Whole genome expression profiling of 40 healthy human twins (20 monozygotic, 20 dizygotic) Keywords: heritability test

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3630
Platform:: GPL570
40 Samples

Download data: CEL, CHP

Series

Accession:: GSE7821

ID:: 200007821

Select item 363011.

Monozygotic and dizygotic twin pairs: intestinal mucosa

Analysis of healthy intestinal mucosa biopsies from 10 monozygotic and 10 dizygotic twin pairs. Barrier organs such as the gut are exposed to continual environmental challenge. Results provide insight into genetic and non-genetic determinants of gene expression.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 gender, 2 genotype/variation, 20 other sets

Platform:: GPL570
Series:: GSE7821
40 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS3630

ID:: 3630

Select item 20000635012.

Transcriptomic profiling of the livers of blue catfish (Ictalurus furcatus) after infection with Edwardsiella ictaluri

(Submitter supplied) We have utilized a high-density oligonucleotide microarray for catfish in order to study the transcriptomic responses of blue catfish following infection with E. ictaluri and to identify and develop important immune-related markers for future characterization and genetic mapping. Microarray analysis of the transcriptome profile of the blue catfish liver following infection with the Gram negative bacterium led to the identification of 103 differentially expressed transcripts. more...