Similar studies for GEO DataSets (Select 200185645) - GEO DataSets

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Items: 4

Select item 2001856451.

Microarray data from patients samples with triple negative breast cancer

(Submitter supplied) The genomic studies was designed to identify genes differentially expressed in tumor versus normal breast tissue. We aimed at identifying novel Antibody Drug Conjugate (ADC) targets that could be used to treat Triple Negative Breast Cancer (TNBC). Comparative genomic studies between normal breast and TNBC tissues, together with proteomic and bioinformatic analyses resulted in the elaboration of a catalog of potential ADC targets.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
16 Samples

Download data: CEL

Series

Accession:: GSE185645

ID:: 200185645

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001419252.

Gene expression data from human breast cancer MDA-MB-231 cells treated with siRNAs targeting long non-coding RNA TMPO-AS1

(Submitter supplied) To examine the role of long non-coding RNA TMPO-AS1 in breast cancer, MDA-MB-231 cells were treated with siRNAs targeting TMPO-AS1 (siTMPO-AS1) or control siRNA (siControl). 3 samples

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL23126
3 Samples

Download data: CEL, CHP

Series

Accession:: GSE141925

ID:: 200141925

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001161623.

Comparative analysis of gene expression of SLC3A2 monoallelic knockout and wild type clones

(Submitter supplied) By employing a global gene expression profiling, we performed analysis of the molecular pathways which are deregulated in SLC3A2 monoallelic knockout clone generated from the head-and-neck cancer cell line Cal33 via CRISPR/Cas9 approach. Both non-irradiated and irradiated with 4Gy samples were compared.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL20844
12 Samples

Download data: TXT

Series

Accession:: GSE116162

ID:: 200116162

Select item 2000470794.

Expression data of patient-derived triple negative breast cancer xenograft tumors

(Submitter supplied) Triple negative breast cancer (TNBC) is an aggressive subtype that lack targeted clinical therapies. In addition, TNBC is heterogeneous and was recently further sub-classified into seven TNBC subtypes that displayed unique gene expression patterns. To develop therapeutic treatment regimens, we established seven patient-derived xenograft models from TNBC tumors. These xenograft models not only retained the histology and clinical markers of the corresponding patient tumors, but also bearing the same mutations and deletions identified in the patient tumors. more...