Similar studies for GEO DataSets (Select 200134548) - GEO DataSets

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Items: 4

Select item 2001345481.

RNA sequencing of splenic B cell populations prevalent in Py-infected mice

(Submitter supplied) Purpose: To peform genome wide transcriptomic analyses and compare the expression profile among Plasmablasts, activated B cells and resting B cells obtained form the spleens of Plasmodium yoelli infected mice on day 10

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21626
12 Samples

Download data: CSV

Series

Accession:: GSE134548

ID:: 200134548

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001549102.

Mouse B cells responding to Plasmodium yoelii infection

(Submitter supplied) This study was designed to capture single cell transcriptomic and BCR repertoire information among subsets of B cells activated during rodent malaria

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21103
3 Samples

Download data: H5

Series

Accession:: GSE154910

ID:: 200154910

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001327963.

Plasmodium yoelii Erythrocyte Binding-like Protein Modulates Host Cell Membrane Structure, Immunity, and Disease Severity

(Submitter supplied) Erythrocyte binding-like (EBL) proteins are known to play an important role in malaria parasite invasion; however, any roles in regulating host immune responses remain unknown. Here we show that an amino acid substitution (C741Y) in the protein trafficking domain of Plasmodium yoelii EBL (PyEBL) changes host immune response and disease severity, but not invasion of red blood cells (RBCs) as suggested previously. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
11 Samples

Download data: XLSX

Series

Accession:: GSE132796

ID:: 200132796

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000852054.

Expansion of an FCRL5+ B cell subset resembling atypical memory B cells in an animal model of malaria

(Submitter supplied) Background: In human malaria, parasites of the genus Plasmodium elicit expansion of atypical memory B cells (atMBCs), which lack the classical markers CD21 and CD27. We have identified a putative population of analogous B cells in a murine model of infection with P. chabaudi, delineated by the marker FCRL5. We performed RNA-Seq on FCRL5+ and FCRL5- B cells sorted from infected mice, so as to characterize the transcriptional profile of these cells and permit comparison to atMBCs in humans. more...