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Links from GEO DataSets

Items: 7

1.

Gene expression of Natural Killer cell-primed monocytes and their subsequent derived dendritic cells

(Submitter supplied) Transcriptome analysis of monocytes directly exposed to cell-to-cell contact with Natural Killer (NK) cells or separated by a transwell membrane and their subsequent monocyte-derived dendritic cells. The role of Natural Killer (NK) cells in the early differentiation of monocytes into dendritic cells (DCs) is poorly understood. Their interaction is thought to be restricted to a bilateral cross talk of soluble cytokines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
30 Samples
Download data: CEL, CHP, XLS
Series
Accession:
GSE116487
ID:
200116487
2.

Gene profiling analysis of mouse splenic DC subpopulations

(Submitter supplied) To characterize differences between BALB/c splenic CD11cintB220+Gr1+ PDCs (plasmacytoid dendritic cells), CD11cintB220+CD49b+ IKDCs (interferon producing killer-dendritic cells), and CD11chighB220- cDCs (conventional dendritic cells), we performed gene expression profile analysis using Affymetrix chips. We FACS-sorted BALB/c spleen DC subpopulations. Comparison of differentially expressed genes between IKDCs and cDCs vividly revealed selective expression of multiple NK-related genes in IKDCs . more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS1654 GDS1657 GDS1658
Platforms:
GPL82 GPL83 GPL81
18 Samples
Download data
Series
Accession:
GSE3691
ID:
200003691
3.
Full record GDS1658

Dendritic cell subpopulations: spleen (MG-U74C)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL83
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1658
ID:
1658
4.
Full record GDS1657

Dendritic cell subpopulations: spleen (MG-U74B)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL82
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1657
ID:
1657
5.
Full record GDS1654

Dendritic cell subpopulations: spleen (MG-U74A)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL81
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1654
ID:
1654
6.

CD56dim NK cell gene signature in melanoma patients with better and worse clinical outcomes

(Submitter supplied) Natural killer (NK) cells are innate cytotoxic and immunoregulatory lymphocytes that have a central role in anti-tumor immunity and play a critical role in mediating cellular immunity in advanced cancer immunotherapies, such as dendritic cell (DC) vaccines. Our group recently tested a novel recombinant adenovirus-transduced autologous DC-based vaccine that simultaneously induces T cell responses against three melanoma-associated antigens for advanced melanoma patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL25998
41 Samples
Download data: RCC, TXT
Series
Accession:
GSE124574
ID:
200124574
7.

Vitamin A-treated NK cells reduce IFN-γ production and support regulatory T cell differentiation

(Submitter supplied) Vitamin A induces changes in NK cell transcriptome, phenotype and function
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL32874
6 Samples
Download data: CEL
Series
Accession:
GSE218594
ID:
200218594
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Supplemental Content

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