Similar studies for GEO DataSets (Select 200087030) - GEO DataSets

Select item 2000870301.

Nipple fibroblast gene expression profile

(Submitter supplied) The nipple is an example of specialized epidermis. The unique epidermal stratification and gene expression is induced and maintained by developmental distinct fibroblast populations. To identify specific signaling modules involved in the maintenance of nipple epidermis we used gene expression profiling of purified fibroblast populations from a murine model of nipple skin formation

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL16570
6 Samples

Download data: CEL

Series

Accession:: GSE87030

ID:: 200087030

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000176542.

Analysis of Gene Expression in PTHrP-/- Mammary Buds

(Submitter supplied) Analysis of Gene Expression in PTHrP-/- Mammary Buds Supports a Role for BMP Signaling and MMP2 in the Initiation of Ductal Morphogenesis. Parathyroid hormone-related protein (PTHrP) acts on the mammary mesenchyme and is required for proper embryonic mammary development. In order to understand PTHrP’s effects on mesenchymal cells, we profiled gene expression in WT and PTHrP-/- mammary buds, and in WT and K14-PTHrP ventral skin, at E15.5. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL339
15 Samples

Download data: CEL, TXT

Series

Accession:: GSE17654

ID:: 200017654

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Select item 2000068673.

Expression data in the absence of Notch1 in hair follicles

(Submitter supplied) Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In addition, the ratio of melanocytes to keratinocytes is greatly reduced. Microarray was performed to study downstream mechanism of Notch1-deficiency Keywords: genetic modification

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2848
Platform:: GPL1261
6 Samples

Download data: CEL

Series

Accession:: GSE6867

ID:: 200006867

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Select item 28484.

Notch1 deficiency effect on hair follicles

Analysis of Notch1-deficient hair follicles from the skin of transgenic animals. Results provide insight into the molecular mechanisms underlying the lowered mitotic index and increased apoptosis observed in Notch1-deficient hair follicles.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 other, 2 strain sets

Platform:: GPL1261
Series:: GSE6867
6 Samples

Download data: CEL

DataSet

Accession:: GDS2848

ID:: 2848

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000810725.

Gene expression from human keratinocytes isolated from limited systemic sclerosis (lcSSc) and diffuse systemic sclerosis (dcSSc) skin biopsy

(Submitter supplied) Systemic sclerosis (SSc) is a rare but devastating disease of fibrosis impacting the dermis and multiple organ systems. The prevalence ranges from 4 to 489 cases per million individuals with ten year mortality rates reported around 18 percent. Survival is related to the extent of skin involvement, yet the precise mechanisms driving skin fibrosis in SSc remain unknown. In this study, we analyzed the shared and unique transcriptomic profiles of SSc and normal keratinocytes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL17692
20 Samples

Download data: CEL, TXT

Series

Accession:: GSE81072

ID:: 200081072

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Select item 2000041646.

Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans

(Submitter supplied) BACKGROUND: When resources are scant, C. elegans larvae arrest as long-lived dauers under the control of insulin/IGF- and TGFbeta-related signaling pathways. : We have identified genes that show different levels of expression in a comparison of wild-type L2 or L3 larvae (non-dauer) to TGFbeta mutants at similar developmental stages undergoing dauer formation. Many insulin/IGF pathway and other known dauer regulatory genes have changes in expression that suggest strong positive feedback by the TGFbeta pathway. more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

4 related Platforms
10 Samples

Download data

Series

Accession:: GSE4164

ID:: 200004164

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Select item 2000366307.

Transcriptomal effects of four-day exposure to estradiol on mouse primary culture urogenital sinus mesenchymal cells of fetal mouse prostate

(Submitter supplied) Developmental exposure of mouse fetuses to estrogens results in dose-dependent permanent effects on prostate morphology and function. Fetal prostatic mesenchyme cells express estrogen receptor alpha (ERα) and androgen receptors and convert stimuli from estrogens and androgens into signaling to regulate epithelial cell proliferation and differentiation. To obtain mechanistic insight into the role of different doses of estradiol (E2) in regulating mesenchymal cells, we examined E2-induced transcriptomal changes in primary cultures of fetal mouse prostate mesenchymal cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
9 Samples

Download data: CEL, CHP

Series

Accession:: GSE36630

ID:: 200036630

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Select item 2000168548.

Expression data from estradiol-treated fetal urogenital sinus mesenchyme cells

(Submitter supplied) Developmental estrogen exposure causes permanent alterations to mouse prostate development. Fetal prostatic mesenchyme cells regulate epithelial cell proliferation and differentiation, and alterations to mesenchymal regulation of prostate epithelial cell proliferation and differentiation may lead to permanent changes in gland structure and function. Our goal was to understand how mesenchymal cells convert estrogen signaling to stimuli that affect epithelial cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL339
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE16854

ID:: 200016854

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Select item 2000237249.

Genes differentially regulated by the glucocorticoid receptor in developing skin of the GR knock out and wt embryos.

(Submitter supplied) To understand the transcriptional program by which GR regulates skin development, we performed a microarray analysis using the skin of E18.5 GR-/- and GR+/+ mouse embryos.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
8 Samples

Download data: CEL

Series

Accession:: GSE23724

ID:: 200023724

PubMed Full text in PMC Similar studies Analyze with GEO2R

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