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Links from GEO DataSets

Items: 8

1.

Transcriptome profiles comparison between the B220+, CD27- and CD27+ NK cell subset

(Submitter supplied) The cell lineage origin of interferon-producing killer dendritic cells (IKDC), which exhibit prominent anti-tumoral activity, has been subject to debate. Although IKDC were first described as a cell type exhibiting both pDC and NK cell properties, the current view reflects that IKDC merely represent activated NK cells expressing B220, which were thus renamed B220+ NK cells. Herein, we further investigate the lineage relationship of B220+ NK cells with regards to other NK cell subsets. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
9 Samples
Download data: TXT
Series
Accession:
GSE34237
ID:
200034237
2.

Gene profiling analysis of mouse splenic DC subpopulations

(Submitter supplied) To characterize differences between BALB/c splenic CD11cintB220+Gr1+ PDCs (plasmacytoid dendritic cells), CD11cintB220+CD49b+ IKDCs (interferon producing killer-dendritic cells), and CD11chighB220- cDCs (conventional dendritic cells), we performed gene expression profile analysis using Affymetrix chips. We FACS-sorted BALB/c spleen DC subpopulations. Comparison of differentially expressed genes between IKDCs and cDCs vividly revealed selective expression of multiple NK-related genes in IKDCs . more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS1654 GDS1657 GDS1658
Platforms:
GPL82 GPL83 GPL81
18 Samples
Download data
Series
Accession:
GSE3691
ID:
200003691
3.
Full record GDS1658

Dendritic cell subpopulations: spleen (MG-U74C)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL83
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1658
ID:
1658
4.
Full record GDS1657

Dendritic cell subpopulations: spleen (MG-U74B)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL82
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1657
ID:
1657
5.
Full record GDS1654

Dendritic cell subpopulations: spleen (MG-U74A)

Analysis of three dendritic cell (DC) subpopulations from BALB/c spleens: interferon-producing killer DCs (IKDCs), plasmacytoid DCs (PDCs), and conventional DCs (cDCs). Results identify IKDCs as a distinct DC lineage and provide insight into the role of IKDCs in linking innate and adaptive immunity.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 cell type sets
Platform:
GPL81
Series:
GSE3691
6 Samples
Download data
DataSet
Accession:
GDS1654
ID:
1654
6.

Genome-wide analysis of atypical NK cell subset in mouse model of Systemic Lupus Erythematosus (SLE)

(Submitter supplied) Exploratory study to identify genome-wide changes in expression between conventional NK cells isolated from B6 WT and NK1.1+ cells from TLR7tg mice
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
6 Samples
Download data: TXT
Series
Accession:
GSE63829
ID:
200063829
7.

Comparison of mouse NK cell subsets defined by CD27 and CD11b expression

(Submitter supplied) Previous reports have defined three subsets of mouse NK cells on the basis of the expression of CD27 and CD11b. The developmental relationship between these subsets was unclear. To address this issue, we evaluated the overall proximity between mouse NK cell subsets defined by CD27 and CD11b expression using pangenomic gene expression profiling. The results suggest that CD27+CD11b-, CD27+CD11b+ and CD27-CD11b+ correspond to three different intermediates stages of NK cell development.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
6 Samples
Download data: CEL
Series
Accession:
GSE13229
ID:
200013229
8.

Expression Data from NKDxIL15tg and IL15 tg NK cells

(Submitter supplied) NK cells from NKDxIL15tg mice spleens and bone marrow were purified by FACS. NK cells from IL15tg mice spleens were purified by FACS. Gene expression differences were analyzed to identify genes involved in NK cell development. Keywords: cell type comparison
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
9 Samples
Download data: CEL
Series
Accession:
GSE10365
ID:
200010365
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