Similar studies for GEO DataSets (Select 200018905) - GEO DataSets

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Items: 12

Select item 2000189051.

Genome-wide analysis of alternative splicing evolution among Mus subspecies

(Submitter supplied) We studied the evolution of alternative splicing in the early stages of species divergence in the house mouse.

Organism:: Mus musculus domesticus; Mus musculus musculus; Mus musculus castaneus; Mus spretus

Type:: Expression profiling by high throughput sequencing

4 related Platforms
7 Samples

Download data: SAM

Series

Accession:: GSE18905

ID:: 200018905

PubMed Similar studies SRA Run Selector

Select item 2000190862.

Exon-based clustering of tumor transcriptomes reveals alternative exons associated with metastasis in breast cancer

(Submitter supplied) Exonic profiling is an emerging topic in disease-associated transcriptome analysis, but is still facing major limitations. In this study, we performed a microarray-based analysis of the transcriptome at the exon level of mouse primary mammary tumors having different abilities to give rise to metastases. First, we developed a bioinformatics platform and used a stringent algorithm to identify 679 genes with differentially expressed exons in primary tumors of the 4T1 mouse model of mammary tumor progression. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6193
12 Samples

Download data: CEL

Series

Accession:: GSE19086

ID:: 200019086

Select item 2000025973.

Contrasting patterns of expression divergence in early and late stages of population divergence in mice

(Submitter supplied) We compared gene expression differences in the polytypic species complex Mus musculus (Mus musculus musculus, Mus musculus domesticus, Mus musculus castaneus and Mus musculus ssp) with that of Mus spretus via oligonucleotide microarrays representing more than 20,000 genes. Analysis of the results by two way ANOVA statistics suggests that the most genes with significant differences in expression levels among the subspecies are found in liver and kidney and the least in testis. more...

Organism:: Mus musculus; Mus spretus

Type:: Expression profiling by array

Platform:: GPL1942
72 Samples

Download data

Series

Accession:: GSE2597

ID:: 200002597

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000024714.

Differential expression in testis in 4 house mouse species

(Submitter supplied) RNA from testis from 4 mus musculus species was hybridized on affymetrix gene chip U74Av2. Subspecies-specific differences in expression level were then extracted by conditioning on outcomes to cases where the expression in one subspecies differed significantly from all others but these did not differ significantly among each other. Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1884
Platform:: GPL81
8 Samples

Download data

Series

Accession:: GSE2471

ID:: 200002471

Select item 18845.

Testes of various subspecies

Expression profiling of testes from subspecies castaneus, domesticus, musculus, and a strain from Iran (BID).

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 strain sets

Platform:: GPL81
Series:: GSE2471
8 Samples

Download data

DataSet

Accession:: GDS1884

ID:: 1884

Select item 2000093386.

Expression data from Mus musculus subspecies and their F1 hybrids for 3 tissues (brain, liver, testis)

(Submitter supplied) We have studied different subspecies of the house mouse (M. m. musculus, M. m. domesticus and M. m. castaneus) and their reciprocal F1 hybrids to estimate the within-locus mode of inheritance for subspecies differences in gene expression in three tissues (brain, liver, testis) of male mice. This study investigates mode of inheritance in crosses at a larger taxonomic distance than have been previously systematically investigated. more...

Organism:: Mus musculus; Mus musculus musculus x M. m. domesticus; Mus musculus musculus x Mus musculus castaneus; Mus musculus domesticus; Mus musculus musculus; Mus musculus castaneus

Type:: Expression profiling by array

Platform:: GPL1261
42 Samples

Download data: CEL

Series

Accession:: GSE9338

ID:: 200009338

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000413387.

The evolutionary landscape of alternative splicing in vertebrate species

(Submitter supplied) How species with similar repertoires of protein coding genes differ so dramatically at the phenotypic level is poorly understood. From comparing the transcriptomes of multiple organs from vertebrate species spanning ~350 million years of evolution, we observe significant differences in alternative splicing complexity between the main vertebrate lineages, with the highest complexity in the primate lineage. more...

Organism:: Anolis carolinensis; Xenopus tropicalis; Gallus gallus; Mus musculus; Tetraodon nigroviridis

Type:: Expression profiling by high throughput sequencing

5 related Platforms
21 Samples

Download data: BW, TXT

Series

Accession:: GSE41338

ID:: 200041338

PubMed Similar studies SRA Run Selector

Select item 2000314548.

Species-specific splicing differences are primarily governed by changes in cis-acting sequences

(Submitter supplied) We assessed whether human transcripts expressed in an aneuploid mouse that carries human chromosome 21 (HsChr21) are spliced in a human-specific or mouse-specific fashion. In almost all cases, human-specific alternative splicing is maintained in the mouse nucleus. Species-specific splicing therefore appears to be primarily directed by cis-acting elements, rather than changes in the levels or activities of trans-acting factors.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL9052 GPL9185
6 Samples

Download data: BOWTIE

Series

Accession:: GSE31454

ID:: 200031454

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000854589.

Filtering of RNA-seq datasets and differences between cell types in global coordination of splicing and proportion of highly expressed genes

(Submitter supplied) The goal of this study was to investigate whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA-seq transcriptome profiles of 8 different purified mouse cell types. We found that different cell types vary in proportion of highly expressed genes and the number of alternatively spliced transcripts expressed per gene, and that the cell types that express more variants of alternatively spliced transcripts per gene are those that have higher proportion of highly expressed genes. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Third-party reanalysis

Download data: DIFF, FPKM_TRACKING, TXT

Series

Accession:: GSE85458

ID:: 200085458

PubMed Full text in PMC Similar studies

Select item 20011195710.

Expression data of E7.5 primary germ layers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL1261 GPL13112
6 Samples

Download data: CEL, TXT

Series

Accession:: GSE111957

ID:: 200111957

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20011195511.

Whole-transcriptome splicing profiling of embryonic day (E)7.5 mouse primary germ layers [RNA-seq]

(Submitter supplied) Alternative splicing (AS) and alternative promoter (AP) usage expand the repertories of mammalian transcriptome profiles and thus diversify gene functions. However, our knowledge about the extent and functions of AS and AP usage in mouse early embryogenesis remains elusive. Here, by performing whole-transcriptome splicing profiling with high-throughput next generation sequencing, we report that AS extensively occurs in embryonic day (E) 7.5 mouse primary germ layers, and may be involved in multiple developmental processes. more...