Related DataSets for GEO DataSets (Select 4769) - GEO DataSets

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Select item 47691.

Radiation chimera model: Trp53-null mammary tumors arising from irradiated, TGFb1 heterozygote hosts

Analysis of Trp53-null tumors arising from Tgfb1+/- hosts cleared of mammary gland epithelia, irradiated, then transplanted with nonmalignant Trp53-null mammary tissue. TGF-β drives EMT and is highly induced by IR. Results provide insight into host biology contributions to radiation carcinogenesis.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 protocol sets

Platform:: GPL1261
Series:: GSE42742
24 Samples

Download data: CEL

DataSet

Accession:: GDS4769

ID:: 4769

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 24552.

Photoreceptor-specific nuclear receptor NR2E3 ectopic expression effect on NRL null retinas

Analysis of 4 week-old neural retinal leucine zipper (NRL) null retinas expressing photoreceptor-specific nuclear receptor (NR2E3) from the cone-rod homeobox (CRX) promoter. NRL, NR2E3, and CRX control photoreceptor differentiation. Results provide insight into the molecular function of NR2E3.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 strain sets

Platform:: GPL1261
Series:: GSE5338
8 Samples

Download data: CEL

DataSet

Accession:: GDS2455

ID:: 2455

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 24423.

Insulin-like growth factor-I decrease effect on the liver

Analysis of livers of animals with decreased serum insulin-like growth factor-I (IGF-I) levels. The liver is the major source of serum IGF-I. The level of serum IGF-I is correlated to bone mineral density (BMD) and fracture risk. Results provide insight into the relationship between IGF-I and BMD.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 other, 2 strain sets

Platform:: GPL1261
Series:: GSE5959
6 Samples

Download data: CEL

DataSet

Accession:: GDS2442

ID:: 2442

Select item 24334.

Limbal and central corneal epithelial basal cell comparison

Analysis of microdissected resting limbal epithelial basal cells (LE) and central corneal epithelial (CE) basal cells of the eye. LE are enriched in corneal epithelial stem cells, CE in transient amplifying cells. Results provide insight into the molecular nature of the two basal cell populations.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 8 individual, 2 tissue sets

Platform:: GPL1261
Series:: GSE4098
16 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2433

ID:: 2433

Select item 24205.

Myoblast differentiation and p53 family members

Analysis of mock and deltaNp73alpha-expressing C2C12 myoblasts 6 and 24 hours after shifting the cells to a differentiation medium. DeltaNp73alpha, a p73alpha isoform, functions as a transdominant inhibitor of other p53 family members, interfering with multiple developmental programs.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 cell line, 3 time sets

Platform:: GPL1261
Series:: GSE5447
6 Samples

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DataSet

Accession:: GDS2420

ID:: 2420

Select item 24126.

Myotubes differentiated in vitro

Analysis of C2C12 skeletal myoblasts induced to differentiate into myotubes in vitro. Results provide insight into the role of nuclear envelope transmembrane proteins in myogenesis.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 development stage sets

Platform:: GPL1261
Series:: GSE4694
6 Samples

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DataSet

Accession:: GDS2412

ID:: 2412

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 24117.

Transcription factor PU.1 knockdown effect on hematopoietic stem cells

Analysis of preleukemic hematopoietic stem cells from animals knocked down for the transcription factor PU.1. PU.1 knockdown leads to acute myeloid leukemia in the animal. Results provide insight into the molecular changes preceding malignant transformation.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 protocol sets

Platform:: GPL1261
Series:: GSE5654
6 Samples

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DataSet

Accession:: GDS2411

ID:: 2411

Select item 24108.

Edema toxin effect on macrophage cell line: time course

Analysis of RAW 264.7 macrophage cells treated with edema toxin (EdTx) for 3 or 6 hours. EdTx is an adenylyl cyclase enzyme produced by Bacillus anthracis. It converts ATP to cAMP, resulting in interstitial edema in anthrax patients. Results provide insight into the effect of EdTx in the host cell.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 agent, 3 time sets

Platform:: GPL1261
Series:: GSE4712
21 Samples

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DataSet

Accession:: GDS2410

ID:: 2410

Select item 24089.

B cell-activating factor of the TNF family effect on B cells

Analysis of total and polysomal RNAs from B cells stimulated with B cell-activating factor of the TNF family (BAFF). BAFF promotes B cell survival. Results provide insight into the signaling mechanisms underlying BAFF-mediated B cell survival.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 protocol sets

Platform:: GPL1261
Series:: GSE5985
4 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2408

ID:: 2408

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 239810.

Hematopoietic cells at various stages of differentiation

Analysis of hematopoietic stem cells (HSCs), progenitor cells (HPCs), and granulocytes. Short-term (ST) and long-term (LT) repopulating HSCs examined. Results provide insight into the basis of the differences observed in cloning efficiency of each cell type in somatic cell nuclear transfer.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 development stage sets

Platform:: GPL1261
Series:: GSE5677
4 Samples

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DataSet

Accession:: GDS2398

ID:: 2398

Select item 239111.

PGC-1alpha transcriptional coactivator null mutation effect on the brain striatum

Analysis of brain striatum of PGC-1alpha transcriptional coactivator null mutants. PGC-1alpha regulates several metabolic processes. Altered energy metabolism is implicated in Huntington's disease (HD). Results provide insight into the role of PGC-1alpha in HD pathogenesis.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE5786
6 Samples

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DataSet

Accession:: GDS2391

ID:: 2391

Select item 239012.

Male germ cells

Analysis of four spermatic subpopulations: type A and type B spermatogonia, pachytene spermatocytes, and round spermatids. The X and Y chromosomes are subject to meiotic sex chromosome inactivation in the mammalian male germline. Results provide insight into the extent of postmeiotic X silencing.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 cell type sets

Platform:: GPL1261
Series:: GSE4193
8 Samples

Download data: CEL

DataSet

Accession:: GDS2390

ID:: 2390

Select item 238713.

Oocyte and one-cell embryo polysomal mRNA

Analysis of the polysomal maternal mRNA (MmRNA) populations of oocytes and late one-cell stage embryos. Results provide insight into the mechanisms that regulate the stage-specific translation of MmRNAs in early development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 development stage sets

Platform:: GPL1261
Series:: GSE3962
8 Samples

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DataSet

Accession:: GDS2387

ID:: 2387

Select item 237114.

Dominant negative thyroid hormone receptor expression and PPARalpha activation effect on the heart

Analysis of hearts of dominant negative thyroid hormone receptor (TR) transgenics after treatment with the peroxisome proliferators activated receptor alpha (PPARalpha) agonist WY14643. Results provide insight into the crosstalk between TR and PPARalpha in the heart.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 strain sets

Platform:: GPL1261
Series:: GSE3067
28 Samples

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DataSet

Accession:: GDS2371

ID:: 2371

Select item 235915.

Interferon regulatory factor 6 null mutation effect on the skin

Analysis of skins of interferon regulatory factor 6 (IRF6) null mutants at embryonic day 17.5. Genetic variations in IRF6 are associated with cleft lip and palate in humans. Results provide insight into the role of IRF6 in epidermal development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE5800
6 Samples

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DataSet

Accession:: GDS2359

ID:: 2359

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 234416.

Bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum comparison

Analysis of three regions of the brain that are dopamine targets and associated with addiction: bed nucleus of the stria terminalis (BNST), nucleus accumbens, and dorsal striatum. Tissues excised from the brains of 12-week-old C57BL/6J males.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 tissue sets

Platform:: GPL1261
Series:: GSE5763
9 Samples

Download data: CEL

DataSet

Accession:: GDS2344

ID:: 2344

Select item 231617.

Gata4 heterozygous mutant heart response to pressure overload

Analysis of pressure-overloaded (PO) heart ventricles of animals heterozygous for the second exon deletion of Gata4, a transcription factor. PO induced by transverse aortic constriction. Results provide insight into the role of Gata4 in the regulation of pathways necessary for cardiac hypertrophy.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 strain, 2 stress sets

Platform:: GPL1261
Series:: GSE5500
21 Samples

Download data: CEL

DataSet

Accession:: GDS2316

ID:: 2316

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 230018.

Germinal vesicle stage and metaphase II stage oocyte comparison

Comparison of oocytes at the germinal vesicle stage (GV) to those at the metaphase II (MII) stage. GV-stage oocytes are transcriptionally silent. Results show that the destruction of transcripts that occurs during oocyte maturation is selective.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 development stage sets

Platform:: GPL1261
Series:: GSE5668
6 Samples

Download data: CEL

DataSet

Accession:: GDS2300

ID:: 2300

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 228819.

Lactoperoxidase effect on the small intestine

Analysis of small intestines of animals 3 hours after ingesting bovine lactoperoxidase (LPO). LPO is a component of milk and exhibits antiviral activities as well as immuno-modulatory effects. Results provide insight into the effect of LPO on the digestive tract.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 agent sets

Platform:: GPL1261
Series:: GSE5562
9 Samples

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DataSet

Accession:: GDS2288

ID:: 2288

Select item 227620.

Embryonic stem cell line response to the conditional expression of neurogenin 3

Analysis of transgenic embryonic stem cells induced with doxycycline to express neurogenin 3 (Ngn3) and differentiated for 3 or 10 days as embryoid bodies. Ngn3 is required for pancreatic islet development. Results provide insight into Ngn3-regulated molecular events during development.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 cell line, 3 development stage, 3 time sets

Platform:: GPL1261
Series:: GSE3653
16 Samples

Download data: CEL

DataSet

Accession:: GDS2276

ID:: 2276

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