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Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross

(Submitter supplied) We studied the cause-effect relationships between the transcriptomics and phenotypic outcomes within the CC-F1 population, which allowed us to identify novel genetic signatures. Our results indicate that Oas1b status as wild type or mutant, and overall Oas1b gene dosage, link with novel innate immune gene signatures that impact specific biological pathways for the control of flavivirus infection and immunity.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL17400
128 Samples
Download data: CEL
Series
Accession:
GSE91003
ID:
200091003

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