GEO DataSet Links for BioProject (Select 244678) - GEO DataSets

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Items: 3

Select item 2000568191.

Effects of knockdown of ROCK1 and ZIPK on gene expression in cultured human vascular smooth muscle cells

(Submitter supplied) Rho-associated kinase (ROCK) and zipper-interacting protein kinase (ZIPK) have been implicated in diverse physiological functions, including smooth muscle contraction, cell proliferation, cell adhesion, apoptosis, cell migration and inflammation. Many aspects of regulation via ROCK and ZIPK, however, remain unclear. In this study, we utilized an siRNA approach to knock down ROCK1 and ZIPK in cultured human arterial smooth muscle cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS5659 GDS5948
Platform:: GPL6244
9 Samples

Download data: CEL

Series

Accession:: GSE56819

ID:: 200056819

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 59482.

Zipper-interacting protein kinase deficiency effect on coronary artery smooth muscle cells in vitro

Analysis of cultured vascular smooth muscle cells following knockdown of zipper-interacting protein kinase (ZIPK). ZIPK is phosphorylated and activated by Rho-associated kinase 1 (ROCK1). These results, together with those from GDS5659, provide further insight into ROCK1 and ZIPK functions.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE56819
6 Samples

Download data: CEL

DataSet

Accession:: GDS5948

ID:: 5948

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 56593.

Rho-associated kinase deficiency effect on coronary artery smooth muscle cells in vitro

Analysis of cultured vascular smooth muscle cells following knockdown of Rho-associated kinase 1 (ROCK1). ROCK1 phosphorylates and activates zipper-interacting protein kinase (ZIPK). These results, together with those from GDSxxxx, provide further insight into ROCK1 and ZIPK functions.