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Examination of DPY-30, DPY-27, SDC-3, DPY-26, DPY-28, SDC-2, and SUMOylated DPY-27 binding in wild type embryos and smo-1 RNAi treated embryos

(Submitter supplied) The essential process of dosage compensation equalizes X-chromosome gene expression between C. elegans XO males and XX hermaphrodites through a dosage compensation complex (DCC) that resembles condensin. The DCC binds to both X chromosomes of hermaphrodites to repress transcription by half. Here we show that post-translational modification by the SUMO conjugation pathway is essential for sex-specific assembly of the DCC onto X. more...
Organism:
Caenorhabditis elegans
Type:
Genome variation profiling by genome tiling array
Platforms:
GPL8135 GPL8134
35 Samples
Download data: GFF, PAIR
Series
Accession:
GSE48413
ID:
200048413

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