GEO DataSets

(Submitter supplied) Understanding and predicting the relationships between genotype and phenotype is often challenging, largely due to the complex nature of eukaryotic gene regulation. A step towards this goal is to map how phenotypic variation evolves through genomic changes that modify gene regulatory interactions. Using the Prairie Rattlesnake (Crotalus viridis) and related species, we integrate mRNA-seq, proteomic, ATAC-seq and whole genome resequencing data to understand how specific evolutionary modifications to gene regulatory network components produce variation in venom gene expression. more...

Organism:

Crotalus viridis; Crotalus concolor; Crotalus lutosus

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL29886 GPL34140 GPL34139

11 Samples

Download data: BW

(Submitter supplied) We generated ATAC-seq data for pre- and post-extraction venom gland samples and H3K4me3, H3K27ac, and CTCF ChIP-seq from post-extraction venom gland samples from the Prairie Rattlesnake to investigate patterns of chromatin accessibility, transcription factor binding, and insulation during venom production, and to identify open promoters and active enhancer regions.

Organism:

Crotalus viridis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL29886

6 Samples

Download data: BW, NARROWPEAK, TXT