graves a dionychaefolia - GEO DataSets

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Items: 13

The following term was not found in GEO DataSets: dionychaefolia.
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Select item 2002410751.

Novel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function

(Submitter supplied) Cardiac metabolic dysfunction is a hallmark of heart failure. Estrogen related receptors ERRalpha and ERRgamma are essential regulators of cardiac metabolism. Therefore, activation of ERR could be a potential theraputic intervention for heart failure. However, in vivo studies demonstrating the potential utility of ERR agonists for heart failure treatment are lacking, as compounds with pharmackinetics appropriate for in vivo use have not been available. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL25947
6 Samples

Download data: TSV

Series

Accession:: GSE241075

ID:: 200241075

PubMed Similar studies

Select item 2002399122.

Novel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function

Organism:: Mus musculus; Rattus norvegicus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL25947
30 Samples

Download data: TXT

Series

Accession:: GSE239912

ID:: 200239912

PubMed Similar studies

Select item 2002438163.

RNAseq of mouse RAW264.7 macrophages with CRISPR deletion of SGK1, SGK3, or SGK1/3 or treated with SGKi Sanofi-14h with or without DMXAA stimulation.

(Submitter supplied) The STING signaling pathway is essential for the innate immune response to DNA viruses and bacteria and is important in tumor immunity. STING binding to cGAMP or to synthetic agonists leads to the activation of the kinase TBK1 which phosphorylates the transcription factor IRF3 which promotes expression of type 1 interferons such as IFNb to block viral activity. Aberrant type 1 IFN expression is associated with human diseases including autoimmunity, HIV, and cancer. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24247
50 Samples

Download data: TXT

Series

Accession:: GSE243816

ID:: 200243816

Select item 2002292564.

Male specific impact of parental care on gene expression in nucleus accumbens

(Submitter supplied) Mammalian infants depend on parental care for survival, with numerous consequences for their behavioral development. We investigated the epigenetic and neurodevelopmental mechanisms mediating the impact of early parental care on social behavior development in prairie voles. We find widespread male specific differential expression of genes related to synaptic transmission and autism in the nucleus accumbens.

Organism:: Microtus ochrogaster

Type:: Expression profiling by high throughput sequencing

Platform:: GPL31149
25 Samples

Download data: CSV

Series

Accession:: GSE229256

ID:: 200229256

PubMed Full text in PMC Similar studies

Select item 2001353785.

RNA-seq of DNMT1 inhibitor treated AML cell lines

(Submitter supplied) Genome wide demethylation by DNMT1 inhibitors GSK3685032 results in up-regulation of epigenetically-silenced genes.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
156 Samples

Download data: TXT

Series

Accession:: GSE135378

ID:: 200135378

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001352076.

Expression profiling and methylation analysis of DNMT1 inhibitor treated AML cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL24676 GPL21145
221 Samples

Download data: IDAT

Series

Accession:: GSE135207

ID:: 200135207

PubMed Full text in PMC Similar studies

Select item 2001352067.

MethylationEPIC array of DNMT1 inhibitor treated AML cell lines - part II

(Submitter supplied) Genome wide demethylation by DNMT1 inhibitor GSK3484862 results in up-regulation of epigenetically-silenced genes. Methylation was assayed for each cell line following DNMT1 inhibitor or vehicle treatment. Global methylation distributions were compared between treated and untreated samples.

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL21145
14 Samples

Download data: IDAT, TXT

Series

Accession:: GSE135206

ID:: 200135206

PubMed Full text in PMC Similar studies

Select item 2001352058.

Epic methylation arrays of DNMT1 inhibitor treated AML cell lines

(Submitter supplied) Genome wide demethylation by DNMT1 inhibitor GSK3685032 results in up-regulation of epigenetically-silenced genes

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL21145
51 Samples

Download data: IDAT, TXT

Series

Accession:: GSE135205

ID:: 200135205

PubMed Full text in PMC Similar studies

Select item 2000569549.

A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hyper-trimethylation

(Submitter supplied) Gene expression changes were analyzed in 2 acute lymphoblastic leukemia cell lines treated with the GSK126 EZH2 inhibitor using Affymetrix Human Genome U133 Plus 2.0 arrays.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
8 Samples

Download data: CEL

Series

Accession:: GSE56954

ID:: 200056954

Select item 20004123910.

Gene expression profiling of two DLBCL cell lines upon shRNA mediated knockdown of EZH2

(Submitter supplied) We studied transcriptional changes by Affymetrix human microarrays in 2 DLBCL cell lines as a result of shRNA mediated knockdown of EZH2. In eukaryotes, epigenetic post-translational modification of histones is critical for regulation of chromatin structure and gene expression. EZH2 is the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) and is responsible for repressing target gene expression through methylation of histone H3 on lysine 27 (H3K27). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE41239

ID:: 200041239

Select item 20004097211.

EZH2 Inhibition as a Therapeutic Strategy for Lymphoma with EZH2 Activating Mutations

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL570 GPL9115
52 Samples

Download data: BED, CEL

Series

Accession:: GSE40972

ID:: 200040972

Select item 20004097112.

Gene expression profiling of EZH2 mutant and wild type DLBCL cell lines treated with EZH2 inhibitor

(Submitter supplied) We studied transcriptional changes by Affymetrix human microarrays in DLBCL cell lines as a result of treatment with GSK126, a potent, highly-selective, SAM-competitive, small molecule inhibitor of EZH2 In eukaryotes, epigenetic post-translational modification of histones is critical for regulation of chromatin structure and gene expression. EZH2 is the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) and is responsible for repressing target gene expression through methylation of histone H3 on lysine 27 (H3K27). more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
40 Samples

Download data: CEL

Series

Accession:: GSE40971

ID:: 200040971

Select item 20004097013.

ChIP-seq analysis of H3K27me3 histone modification in EZH2 mutant and wild type DLBCL cell lines

(Submitter supplied) In eukaryotes, epigenetic post-translational modification of histones is critical for regulation of chromatin structure and gene expression. EZH2 is the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2) and is responsible for repressing target gene expression through methylation of histone H3 on lysine 27 (H3K27). Over-expression of EZH2 is implicated in tumorigenesis and correlates with poor prognosis in multiple tumor types. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9115
6 Samples

Download data: BED

Series

Accession:: GSE40970

ID:: 200040970

PubMed Similar studies SRA Run Selector

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graves a dionychaefolia (13)
GEO DataSets
pyridine nucleotide-disulfide oxidoreductase/dicluster-binding protein [Desulfos...
pyridine nucleotide-disulfide oxidoreductase/dicluster-binding protein [Desulfoscipio gibsoniae]
gi|493569687|ref|WP_006522956.1|

Protein
Homo sapiens beta-1,4-galactosyltransferase 2 (B4GALT2), transcript variant 3, m...
Homo sapiens beta-1,4-galactosyltransferase 2 (B4GALT2), transcript variant 3, mRNA
gi|339276011|ref|NM_001005417.2|

Nucleotide
Rattus norvegicus cAMP responsive element modulator (Crem), transcript variant 5...
Rattus norvegicus cAMP responsive element modulator (Crem), transcript variant 5, mRNA
gi|402746811|ref|NM_001271102.1|

Nucleotide
Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (...
Homo sapiens UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 (B4GALT2) mRNA
gi|4502346|ref|NM_003780.1|

Nucleotide

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