GEO DataSets

(Submitter supplied) To explore how brains change upon species evolution, we generated the first whole central brain comparative single-cell transcriptomic atlases of three closely-related but ecologically-distinct drosophilids: D. melanogaster, D. simulans and D. sechellia. D. melanogaster and D. simulans are cosmopolitan generalists, while the island endemic D. sechellia exhibits extreme niche specialism on the ripe noni fruit of the Morinda citrifolia shrub. more...

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL21306 GPL27544 GPL24063

24 Samples

Download data: MTX, TSV

(Submitter supplied) Somatic embryogenesis (SE) is a useful biotechnological tool to study the morpho-physiological, biochemical and molecular processes during the development of Coffea canephora. Plant growth regulators (PGR) play a key role during cell differentiation in SE. The Auxin-response-factor (ARF) and Auxin/Indole-3-acetic acid (Aux/IAA) are fundamental components involved in the signaling of the IAA. The IAA signaling pathway activates or represses the expression of genes responsive to auxins during the embryogenic transition of the somatic cells. more...

Organism:

Coffea canephora

Type:

Expression profiling by high throughput sequencing

Platform:

GPL26348

12 Samples

Download data: TXT

(Submitter supplied) To characterize the differentially expressed genes in HUVECs between normal, hypoxia/reoxygenation-induced injury and Inulin-type oligosaccharides administration. Performing the Affymetrix Human Transcriptome Array 2.0 (HTA2.0, n=3) assay demonstrated that Hex5 exposure up-regulated genes enriched in cell cycle progression, DNA replication and repair, ubiquitin-mediated proteolysis, apoptosis, MAPK, and the IP3K-mTOR signaling pathway. more...

Organism:

Homo sapiens; Homo

Type:

Expression profiling by array

Platform:

GPL17586

9 Samples

Download data: CEL

(Submitter supplied) Transcriptional profiling of 3 day old virgin male and female adults comparing control male Drosophila melanogaster (MDM) versus male D sechellia (MDS) and comparing control female Drosophila melanogaster (FDM) versus female D sechellia (FDS). Goal was to determine why D sechellia is tolerant to octanoïc acid, the major toxic compound of Morinda citrifolia fruit

Organism:

Drosophila sechellia; Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL6385

8 Samples

Download data: TXT

(Submitter supplied) The dietary specialist fruit fly Drosophila sechellia has evolved to specialize on the toxic fruit of its host plant Morinda citrifolia. Toxicity of Morinda fruit is primarily due to high levels of octanoic acid (OA). Using RNA interference (RNAi), prior work found that knockdown of Osiris family genes Osiris 6 (Osi6), Osi7, and Osi8 led to increased susceptibility to OA in adult D. melanogaster flies, likely representing genes underlying a Quantitative Trait Locus (QTL) for OA resistance in D. more...

Organism:

Drosophila sechellia

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24063

6 Samples

Download data: TXT

(Submitter supplied) Purpose: The recent publication of the fungal mutualist R. irregularis genome facilitated transcriptomic studies. We here wanted to understand the large host range of this fungus, throught its gene regulation in divergent plants Methods: mRNA from Medicago truncatula (legume), Brachypodium distachyon (grass) and Lunularia cruciata (liverwort) in association with R. irregularis were sequenced. Reads were mapped on the genome assembly with the software CLC workbench. more...

Organism:

Medicago truncatula; Rhizophagus irregularis; Brachypodium distachyon; Lunularia cruciata

Type:

Expression profiling by high throughput sequencing

4 related Platforms

12 Samples

Download data: TXT

(Submitter supplied) Background Antennae of fruit flies are the major organs responsible for detecting environmental volatiles, e.g., egg-laying substrates. An adult antenna contains many sensilla full of olfactory sensory neurons, where olfactory receptor (Or) genes are expressed. Each sensory neuron only expresses up to three receptors, making it difficult to estimate expression levels by conventional methods. In this study, we applied Illumina RNA sequencing (RNA-seq) to study the expression levels of Or and other genes in fly antennae. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13304

2 Samples

Download data: FPKM_TRACKING

(Submitter supplied) Drosophila simulans relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. simulans host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...

Organism:

Drosophila simulans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL13306

6 Samples

Download data: FPKM_TRACKING

(Submitter supplied) Drosophila sechellia relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. sechellia host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...

Organism:

Drosophila sechellia

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20000

6 Samples

Download data: FPKM_TRACKING

(Submitter supplied) Drosophila sechellia relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species D. melanogaster and D. simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes were suggested to be associated with the D. sechellia host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. more...

Organism:

Drosophila sechellia

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20000

6 Samples

Download data: FPKM_TRACKING

(Submitter supplied) Asterids is one of the major plant clades comprising of many commercially important medicinal species. One of the major concerns in medicinal plant industry is adulteration/contamination resulting from misidentification of herbal plants. This study reports the construction and validation of a microarray capable of fingerprinting medicinally important species from the Asterids clade.

Organism:

Sambucus nigra; Camellia sinensis; Coffea arabica; Angelica archangelica; Vitex agnus-castus; Trachelospermum jasminoides; asterids; Rehmannia glutinosa; Codonopsis; Valeriana officinalis; Taraxacum officinale; Lonicera japonica; Lycium barbarum; Leonurus cardiaca; Embryophyta; Digitalis purpurea; Platycodon grandiflorus; Symphytum; Cornus; Achillea millefolium; Impatiens; Tetrapanax papyrifer; Scrophularia nodosa; Gardenia jasminoides; Forsythia suspensa; Withania somnifera; Ilex paraguariensis

Type:

Genome variation profiling by array

Platform:

GPL14119

27 Samples

Download data: TXT

(Submitter supplied) Transcriptome analysis of in vitro-produced bovine 2-cell embryos according to their time to the first cleavage. Three time points were established in order to collect all the 2-cell embryos present at each moment to contrast only the two exteme embryo subpopulations: fast against slow.

Organism:

Bos taurus

Type:

Expression profiling by array

Platform:

GPL13226

8 Samples

Download data: TXT

(Submitter supplied) We used a cDNA microarray previously defined for the marine sentinel organism Mytilus galloprovincialis (MytArray1.0) to evaluate the effects of nanomolar doses of combined metal salts (50, 100 and 200 nM mixtures of Cd, Cu and Hg) after 48 hours of mussel exposure. Pointing to the mussel gills, first target of toxic water contaminants and actively proliferating tissue, we found significant dose-related increases of cells with micronuclei and other nuclear abnormalities in the treated mussels, with differences in the bioconcentration of the three metals determined in the mussel pulp by atomic absorption spectrometry. more...

Organism:

Mytilus galloprovincialis

Type:

Expression profiling by array

Platform:

GPL1799

18 Samples

Download data: TXT

(Submitter supplied) Transcriptional profiling of mussel (Mytilus galloprovincialis) digestive gland tissue comparing control tissue with tissue obtained from animals exposed for four days to sublethal amounts of Nickel, Chlorpyrifos, or their mixture. Background: Mixtures of chemicals present in aquatic environments may elicit toxicity due to additive or synergistic effects among the constituents or ‘vice versa’ the adverse outcome may be reduced by antagonistic interactions. more...

Organism:

Mytilus galloprovincialis

Type:

Expression profiling by array

Platforms:

GPL10269 GPL1799

17 Samples

Download data: GPR

(Submitter supplied) The closely related Coffea arabica cultivars ‘Tall Mokka’ and ‘Typica’, with excellent flavor, but differing distinctively in the size of aerial organs, branching pattern and branch numbers. Differential gene expression analysis of shoot tips of arabica coffee cultivars 'Tall Mokka' and 'Typica' were done using Potato cDNA microarray as cross-species platform. Using cross-species microarray hybridization, we identified a prolyl oligopeptidase (CaPOP) gene as differentially expressed between the shoot tips of ‘Tall Mokka’ and ‘Typica’. more...

Organism:

Solanum tuberosum; Coffea arabica

Type:

Expression profiling by array

Platform:

GPL14110

8 Samples

Download data: GPR

(Submitter supplied) Retinoblastoma Y79 cell line was treated with scopoletin in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression profiling in the Y79 cell line. The study identified 1675 up-regulated genes (>1.0 fold) and 1879 down-regulated genes (<-1 fold) in response to scopoletin treatment

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6480

2 Samples

Download data: TXT

(Submitter supplied) Mytilus galloprovincialis (Lmk, 1819) is economically relevant bivalve specie. In Adriatic Sea, periodical temperatures increases define optimal growth conditions for Dinoflagellate spp which can reach high concentrations also in filter-feeding mussels, thus causing potential human health problems. The most commonly used methods for the detection of Diarrhoeic Shellfish Poisoning biotoxins have either a low sensitivity or are too expensive to be used for routine tests. more...

Organism:

Mytilus galloprovincialis

Type:

Expression profiling by array

Platform:

GPL1799

24 Samples

Download data: TXT

(Submitter supplied) Here we show that Drosophila sechellia—a specialist on the fruit of Morinda citrifolia that recently diverged from its generalist sister-species, D. simulans—has rapidly accumulated loss-of-function alleles and reduced gene expression at genes affecting olfaction, detoxification, and metabolism. While D. sechellia increases expression of genes involved with oogenesis and fatty acid metabolism when on its host, many more genes show reduced expression in D. more...

Organism:

Drosophila sechellia; Drosophila melanogaster; Drosophila simulans

Type:

Expression profiling by array

Platforms:

GPL3830 GPL3829

20 Samples

Download data: TXT

(Submitter supplied) Here we show that Drosophila sechellia—a specialist on the fruit of Morinda citrifolia that recently diverged from its generalist sister-species, D. simulans—has rapidly accumulated loss-of-function alleles and reduced gene expression at genes affecting olfaction, detoxification, and metabolism. While D. sechellia increases expression of genes involved with oogenesis and fatty acid metabolism when on its host, many more genes show reduced expression in D. more...

Organism:

Drosophila melanogaster; Drosophila sechellia; Drosophila simulans

Type:

Expression profiling by array

Platform:

GPL3829

24 Samples

Download data: TXT

(Submitter supplied) We examined gene expression profiling of native mussels that were sampled in early summer 2003 from sites of the Venice lagoon area known to be differently affected by chemical pollution: Sites 1 and 2 close to the industrial district of Marghera and Site 3 close to the Lido lagoon outlet. Site 4, a current mussel farm located offshore, has been chosen as source of reference targets for microarray hybridizations. more...

Organism:

Mytilus galloprovincialis

Type:

Expression profiling by array

Platform:

GPL1799

6 Samples

Download data