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Items: 4

1.

FOXP4-mediated induction of PTK7 activates the Wnt/β-catenin pathway and promotes ovarian cancer development

(Submitter supplied) Ovarian cancer (OC) presents a significant challenge in clinical settings due to its difficulty in early diagnosis and its resistance to treatment. FOXP4 is a member of the FOXP subfamily and is involved in various biological processes including embryonic development, cell cycle regulation, and tumorigenesis. Despite its potential role in cancer, the exact function and significance of FOXP4 in OC remain uncertain. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
4 Samples
Download data: TXT
Series
Accession:
GSE242332
ID:
200242332

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Protein kinase 7 regulating extracellular matrix assemblies and intracellular RAC1 and myosin II activities in the mesenchyme is important to Wolffian duct morphogenesis.

(Submitter supplied) Wolffian/epididymal duct morphogenesis highly coordinates with its specialized function of providing microenvironment for sperm maturation. Without normal development of Wolffian duct, male infertility will result. Therefore, it is important to understand the cellular and molecular mechanisms that regulated Wolffian duct morphogenesis. Our previous study showed that mediolateral intercalation of epithelial cells was a major driver of ductal elongation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
8 Samples
Download data: TXT
Series
Accession:
GSE98715
ID:
200098715

PubMed Full text in PMC Similar studies SRA Run Selector

3.

Genome-wide transcriptional analysis of HT1080 cells stably transfected with PTK7 constructs

(Submitter supplied) Full-length membrane PTK7 and its N-terminal and C-terminal proteolytic fragments induced differential transcriptional profiles in HT1080 cells. Pseudokinase PTK7 is an essential regulator of planar cell polarity (PCP) and directional cell motility in the course of vertebrate development and embryogenesis, and regulates both the non-canonical Wnt/PCP and canonical Wnt pathways. In contrast to its well-appreciated, crucial role in embryo development, the functional importance of the intact full-length PTK7 in malignancy is still a matter of debate. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
7 Samples
Download data: TXT
Series
Accession:
GSE53340
ID:
200053340

PubMed Full text in PMC Similar studies Analyze with GEO2R

4.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Homo sapiens
136 DataSets
1879 Series
27 Related Platforms
38399 Samples
Download data
Platform
Accession:
GPL6244
ID:
100006244

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db=gds|term=PTK7%20protein%20tyrosine%20kinase%207|query=14|qty=3|blobid=MCID_672c90f7f3ea77543e3926c9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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