GEO DataSets

(Submitter supplied) Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied. Here, we performed comparative polysome and associated transcriptional profiling analyses to study the dynamics and functional implications of endoplasmic reticulum (ER)-associated protein synthesis in the mouse liver under conditions of obesity and nutrient deprivation.

Organism:

Mus musculus

Type:

Expression profiling by array; Other

Dataset:

GDS4506

Platform:

GPL1261

10 Samples

Download data: CEL, CHP

Analysis of liver endoplasmic reticulum (ER)-associated polysomes from leptin deficient (ob/ob) males after overnight fasting. The liver is critical for metabolic homeostasis. Results provide insight into molecular mechanisms underlying changes in protein metabolism caused by obesity and diabetes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation, 2 protocol sets

Platform:

GPL1261

Series:

GSE39375

10 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4544 Series

40 Related Platforms

58935 Samples

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