GEO DataSets

(Submitter supplied) Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPC). Here, we use high-resolution expression profiling to characterize the early transcriptome changes induced after spinal cord injury, and identify the signals that trigger NSPC proliferation. The analysis delineates a pathway that starts with a rapid and transitory activation of immediate early genes, followed by migration processes and immune response genes, the pervasive increase of NSPC specific ribosome biogenesis factors, and genes involved in stem cell proliferation. more...

Organism:

Xenopus laevis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL22393 GPL17682

111 Samples

Download data: TXT