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Items: 3

1.

Single-cell multi-omics in human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

(Submitter supplied) Clonal hematopoiesis (CH) reflects clonal expansion of blood stem and progenitor cells with somatic mutations. We leveraged multi-modality single-cell sequencing to capture mutation status together with the transcriptome and methylome of CD34+ hematopoietic progenitor cells from five individuals with DNMT3A R882-mutated CH.
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL24247 GPL11154 GPL24676
26 Samples
Download data: CSV, MTX, TSV, TXT, XLSX
Series
Accession:
GSE158067
ID:
200158067

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2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17049 Series
931958 Samples
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Platform
Accession:
GPL24676
ID:
100024676

3.

CH04_1 scRREMseq

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL24676
Series:
GSE158067
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Sample
Accession:
GSM4852369
ID:
304852369

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db=gds|term=GSM4852369[Accession]|query=32|qty=3|blobid=MCID_6731b9a9f73b361c51572a60|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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