GSM4664521[Accession] - GEO DataSets

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Items: 4

Select item 2001541351.

RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs (ChIP-Seq 2)

(Submitter supplied) N6-methyladenosine (m6A) methyltransferase METTL3 mainly mediates mRNA m6A methylation and plays important roles in various biological processes. Here we report a chromatin-based role for METTL3 in heterochromatin integrity regulation in mouse embryonic stem cells (mESCs). We show that in mESCs METTL3 predominantly localizes to one of the most active endogenous retroviruses (ERVs) families, the intracisternal A-type particles (IAPs). more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL21273
62 Samples

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Accession:: GSE154135

ID:: 200154135

PubMed Similar studies SRA Run Selector

Select item 2001262432.

RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing