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Items: 3

1.

Active and repressed chromatin domains exhibit distinct nucleosome segregation during DNA replication

(Submitter supplied) Chromatin domains and their associated structures must be faithfully inherited through cellular division to maintain cellular identity. Yet, accessing the localized strategies preserving chromatin domain inheritance, specifically the transfer of parental, pre-existing nucleosomes with their associated post-translational modifications (PTMs) during DNA replication is challenging in living cells. We devised an inducible, proximity-dependent labeling system to irreversibly mark replication-dependent H3.1 and H3.2 histone-containing nucleosomes at single desired loci in mouse embryonic stem cells such that their fate after DNA replication could be followed. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL24247
27 Samples
Download data: BW, TXT
Series
Accession:
GSE136245
ID:
200136245
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

6h_Plus_Triptolide_1

Organism:
Mus musculus
Source name:
6h release into S-phase, 1uM treatment of Triptolide
Platform:
GPL24247
Series:
GSE136245
Download data: TXT
Sample
Accession:
GSM4043229
ID:
304043229
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db=gds|term=GSM4043229[Accession]|query=1|qty=2|blobid=MCID_661c3208e3fccf29378e0a95|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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