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Items: 3

1.

RNA-Seq data on KMO inhibitor (CHDI-00340246) subchronic treated R6/2 mice.

(Submitter supplied) Dysregulation of the kynurenine (Kyn) pathway has been associated with the progression of Huntington's disease (HD). In particular, elevated levels of the kynurenine metabolites 3-hydroxy kynurenine (3-OH-Kyn) and quinolinic acid (Quin), have been reported in the brains of HD patients as well as in rodent models of HD. The production of these metabolites is controlled by the activity of kynurenine mono-oxygenase (KMO), a mitochondrial outer membrane enzyme which catalyzes the synthesis of 3-OH-Kyn from Kyn. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
46 Samples
Download data: XLSX
Series
Accession:
GSE105158
ID:
200105158

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2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8349 Series
188710 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

R6/2_HD_Cortex_Male_Vehicle_replicate2

Organism:
Mus musculus
Source name:
R6/2, Cortex, Vehicle
Platform:
GPL13112
Series:
GSE105158
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Sample
Accession:
GSM2823489
ID:
302823489

SRA Run Selector

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db=gds|term=GSM2823489[Accession]|query=4|qty=2|blobid=MCID_6734e4532bb64338de0ec3c6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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