GEO DataSets

(Submitter supplied) Primary glioblastoma, representing over 90% of adult glioblastoma, develop rapidly without preexisting lower-grade glioma. We have generated a mouse model of primary glioblastoma driven by a single p53 mutation. These p53-mutant gliomas lose the syntenic region of human chromosome 10q, which is mapped to mouse chr19 and chr7. Loss of mouse chr19, containing Pten, activates PI3K/Akt signaling. Rictor/mTORC2 deletion inhibits Akt signaling, causing a significant delay in p53-mutant driven glioma formation. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL9523

32 Samples

Download data: CEL, TXT

(Submitter supplied) This is identical to GPL1261 but a custom cdf environmnet was used to extract data. The cdf can be found at the link below.

Organism:

Mus musculus

1 DataSet

2 Series

1 Related Platform

36 Samples

Download data: CDF