GSM1599188[Accession] - GEO DataSets

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Items: 4

Select item 2000655171.

Comparative analysis of monocytes from healthy donors, patients with metastatic breast cancer, sepsis or tuberculosis.

(Submitter supplied) Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevance of monocytic-MDSCs (Mo-MDSCs) is unknown. Here we report for the first time an enrichment of functional blood Mo-MDSCs in breast cancer patients before they acquire a typical Mo-MDSC surface phenotype. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5819
Platform:: GPL10558
13 Samples

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Series

Accession:: GSE65517

ID:: 200065517

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 58192.

Metastatic breast cancer and sepsis: monocytes

Analysis of the total population of monocytes from patients with metastatic breast cancer (MBC), sepsis, or tuberculosis. Results provide insight into molecular similarities between monocytes from MBC patients and reprogrammed immunosuppressive monocytes from sepsis patients.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 disease state sets

Platform:: GPL10558
Series:: GSE65517
13 Samples

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DataSet

Accession:: GDS5819

ID:: 5819

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000105583.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...